Vitamin B12 in ampoules: instructions for use

Physico-chemical characteristics

Vitamin B2 (riboflavin) is a water-soluble organic element. It is yellow-orange crystals with a bitter taste.

The substance has a structure that is resistant to various acids and not resistant to alkalis. It is destroyed under the influence of ultraviolet rays.

Riboflavin derivatives are part of a large number of redox enzymes.

Vitamin B2, like other water-soluble complexes, does not have the ability to accumulate in living tissues. In a short period of time, it is almost completely eliminated from the body naturally.

Recovery period

· It is not recommended to touch your face on the first day after injections

· Swelling is possible in the affected areas. It is not recommended to eat salty and spicy foods, so as not to complicate or prolong the recovery period

· At first you should refrain from decorative cosmetics - foundation and powder. It is necessary to exclude lotions and tonics containing alcohol.

· for two weeks you should refrain from visiting the bathhouse, sauna, solarium; in addition, peelings and scrubs are prohibited

· for 3-4 weeks it is not recommended to massage the area where fillers are introduced

After two weeks, the tissues are completely restored, and the result is maximally visible.

main sources

Riboflavin can be synthesized in small amounts in the intestines, but the body’s “own” vitamin B2 is not enough.

To avoid the adverse factors associated with vitamin B2 deficiency, it must be regularly obtained from external sources. A properly formulated diet will help provide the body with vitamin B2.

Riboflavin content in foods of animal origin:

Riboflavin content in plant foods:

Vitamin B2 is used in the food industry to enrich the composition of the product and as a natural coloring agent (additive E101).

In some cases, additional riboflavin is required. Causal factors may include:

• malnutrition;
• dieting;
• increased physical activity;
• diseases;
• elderly age;
• unfavorable environmental conditions.

To maintain and improve the body, additional sources of riboflavin are used for preventive and therapeutic purposes:

• vitamin complexes;
• biologically active additives;
• medicines based on it.

In case of general malaise and the presence of diseases, these drugs are taken as prescribed by a doctor.

Main functions

Vitamin B2 is an active substance that supports the functioning of the entire body. Riboflavin:

• It is a necessary link in redox processes, converts other important components (including vitamins B6, D, folic and nicotinic acids) into active forms.
• Promotes the production of red blood cells, which ensure the internal distribution of oxygen.
• Takes part in the production of antibodies necessary to protect the body from infections.
• Ensures coordinated activity of the nervous system.
• Regulates hormonal function.
• Clears the lungs of toxins.
• Neutralizes free radicals, providing an antioxidant effect.
• Protects the retina of the eyes from UV radiation.
• Prevents the development of cataracts.
• Normalizes the flow of bile.
• Improves the absorption of vitamin B6 and iron.
• Regulates metabolic processes.
• Participates in energy exchange.

Vitamin B2 is an essential component in the human body. A deficiency of this substance leads to serious functional disorders.

Beneficial features

Riboflavin has beneficial effects on health. As a result of taking drugs based on it, the following is noted:

• improvement of general well-being;
• increasing energy potential;
• reduction of irritability and anxiety;
• slowing down age-related changes in the brain;
• improved muscle function, including the heart;
• relief from headaches, migraines;
• optimization of visual functions;
• normalization of blood clotting;
• rapid healing of damaged tissues;
• improvement of the condition of skin, hair, nails;
• increasing the body's resistance.

Doctors recommend that women take vitamin B2 during pregnancy, as this component promotes the proper development of the fetus.

MesoEye C71™

Exclusive solution to aesthetic problems in the periorbital area:

• relief of manifestations of swelling and pastiness in the periorbital area;
• improving skin color, reducing the severity of dark circles under the eyes;
• increased turgor and skin tone in the periorbital area;
• smoothing the macro- and microrelief of the skin;
• reducing the severity of paraorbital hernias.

The mechanism of action of the drug is associated with the normalization of blood and lymph circulation, which prevents the occurrence of congestion in the periorbital area:

1. Normalization of local blood and lymph circulation - reducing microvascular spasm (suppressing the activity of angiotensin-converting enzyme), restoring the normal direction and intensity of blood and lymph flow, reducing the permeability of vascular cells. In total, all this prevents the occurrence of congestion in the periorbital area - direct lymphostimulating effect, reduction of arteriolar spasm, vasoprotection

2. Protection of collagen and elastin fibers, as well as other macromolecular components of the intercellular matrix from the formation of covalent cross-links as a result of glycation. This improves the mechanical properties of the skin (firmness, elasticity), which naturally leads to a reduction in the external manifestations of swelling, improved texture, etc. - improvement in the structural and functional state of the skin, revitalization, lifting.

3. Due to the presence of an opioid peptide (Hexapeptide-17), the drug has lipolytic activity, that is, it promotes a more active breakdown of lipids in subcutaneous adipose tissue - increased physiological liposis.

Compound:

MesoEye C71™ is a bioactive patented formula consisting of PeriOrbital Peptide XP2, Hexapeptide 17 and unstabilized hyaluronic acid of bioenzymatic origin in a composition with vitamins, microelements, amino acids, nucleic acids.

Consumption rate

For full life activity, the amount of riboflavin entering the body must be sufficient.

The daily requirement for this substance is as follows:

With intense physical, mental, emotional stress, as well as with increasing age, the need for riboflavin increases.

Meso-Xanthin F199™

A new generation injectable drug with an epigenetic focus for intensive prevention of photo- and chronoaging of the skin after 25 years.

Meso-Xanthin F199™ at the epigenetic level initiates processes aimed at repairing and maintaining the stability of the DNA nucleotide sequence under conditions of oxidative stress and aging; promotes mechanical stretching and “awakening” of fibroblasts, limiting collagen degradation, activation of productive processes, which leads to restoration of the structure of the cell matrix.

Meso-Xanthin F199™ “rejuvenates” skin cells, increases the “quality of life” of cells and their durability, provides physiological renewal of the skin, restores the antioxidant and immune potential of the skin.

Advantages:

1. A unique patented multicomponent injectable drug, the key component of which is the carotenoid Fucoxanthin, which has a powerful positive epigenetic effect on the proliferation and differentiation of progenitor precursor cells, on the DNA repair of its own stem cells damaged under oxidative stress and during the aging process.

2. “Meso-Xanthin F199™” is an effective specific (selective) EPIGENETIC regulator of gene expression that encodes the most important structural and functional proteins of skin cells

3. A reliable source of effective solutions to aesthetic problems and rehabilitation of the skin of patients with chronic dermatoses. (note, a wide range of applications for solving cosmetic problems and in the complex treatment of various chronic dermatoses. Symbiosis of cosmetology and dermatology).

4. The safety, effectiveness and reliability of Meso-Xanthin F199™ has been confirmed by numerous clinical and fundamental studies and many years of practical experience in different countries.

5. Used in women and men mainly after the age of 25 years.

Main components:

• Fucoxanthin (Fucoxanthin F-199)
• Hyaluronic Acid (molecular weight 3000 kDa, concentration 1.56%)
• growth factors (EGF; bFGF; IGF-2;);
• regulatory peptides (TRX; CG);
• vitamins (A; C; E);
• amino acids;
• nucleic acids;
• coenzymes.

Vitamin B2 deficiency

The lack of a substance in the body affects, first of all, the state of the nervous system and skin. The following symptoms are observed with hypovitaminosis:

• general weakness, lethargy, apathy;
• increased irritability;
• memory impairment;
• sleep disturbance;
• headache;
• low pressure;
• blurred vision;
• photophobia;
• development of conjunctivitis, keratitis, cataracts;
• feeling of weakness and muscle pain;
• pale and dry skin;
• seborrheic dermatitis in the areas of the nose, ears, eyelids;
• the appearance of cracks and ulcers on the lips;
• swelling and hyperemia of the tongue - glossitis;
• prolonged wound healing;
• anemia.

The main reasons that lead to a decrease in riboflavin levels include:

• Lack of dietary sources of vitamin B2.
• Using cooking methods that destroy this component.
• Improper storage of products containing it.
• Diseases of the digestive tract.
• Taking medications that are riboflavin antagonists.
• Alcoholism.

Vitamin B2 deficiency often leads to a deficiency of other water-soluble components. Natural nutritional supplements based on it will help restore the required level of the substance in the body.

Hypervitaminosis

Riboflavin obtained as part of products practically does not accumulate. Its excess is excreted in urine, which turns bright yellow.

Hypervitaminosis can develop due to excessive consumption of substances in medications. This usually occurs when the instructions or recommendations of a specialist for its use are violated.

Against the background of hypervitaminosis, symptoms such as:

• general weakness;
• dizziness;
• numbness of the limbs;
• itching, burning sensation in the arms and legs.

With a significant and prolonged excess of the dosage, the risk of developing diseases such as cerebral insufficiency and fatty liver hepatosis increases.

Indications for use

Riboflavin-based drugs are used for the prevention and treatment of a number of disorders, including:

• vitamin deficiency;
• nervous system disorders;
• deterioration of visual functions;
• conjunctivitis, keratitis, cataracts;
• cheilitis, stomatitis, glossitis;
• skin diseases;
• slow healing wounds;
• gastrointestinal disorders;
• hepatitis, liver cirrhosis;
• diabetes;
• radiation sickness;
• anemia;
• leukemia

Additional intake of riboflavin is indicated for disorders such as:

• decreased absorption of vitamins (including B2) from the gastrointestinal tract;
• intensive removal of organic compounds;
• hypoxia (acute and chronic);
• cardiac and respiratory failure.
• acute infections;
• burn disease;
• frostbite.

It is recommended to use drugs with this substance in combination with medications if you have:

Riboflavin is recommended to be taken in parallel with the use of antibacterial drugs that disrupt the natural intestinal microflora, as well as during phototherapy.

Treatment courses are carried out under the supervision of a specialist.

Restylane®

The Restylane® family of products was developed to ensure that individuality and beauty are achieved in a completely natural way. They are designed to improve the appearance by rejuvenating the skin, smoothing folds and wrinkles, giving additional volume to tissues and improving facial contours. A wide range of possibilities allows you to carry out procedures, fully taking into account the characteristics of each patient.

Restylane is manufactured using patented NASHA™ technology (Q-MED), which minimally stabilizes hyaluronic acid to produce a dense gel. Raw materials are obtained from non-animal sources to ensure biocompatibility of the drugs with tissue after administration. Restylane is a biodegradable drug, which over time, during the life of the body, breaks down and is naturally eliminated from it.

Safety is a very important aspect for patients. RESTYLANE received FDA approval following successful safety, efficacy and comparative clinical studies. Restylane is manufactured in Sweden by Q-Med AB.

Features of interaction with other substances

The riboflavin content decreases when taking:

• ethanol;
• barbiturates;
• phenothiazine;
• antidepressants (tricyclics);
• tubular secretion blockers;
• thyroid hormones.

Vitamin B2 absorption increases when taken in parallel:

• probenecid;
• anticholinergic drugs.

Compatible with riboflavin:

• antihypoxants;
• anabolic agents;
• medications to treat anemia.

Vitamin B2 prevents the side effects of chloramphenicol (manifested by impaired hematopoiesis, optic neuritis).

When riboflavin is combined with tetracyclines, the activity of the latter may decrease.

BIO-R is a new generation biorevitalizant

Long-acting biorevitalizant based on high-molecular hyaluronic acid of non-animal origin.

Advantages of the drug: Effective - Gives visible and lasting results.

Safe: Available in sterile syringes for single use, registered (certified) and approved for use in the Russian Federation. The studies carried out did not reveal any side effects or reactions. Replenishes hyaluronic acid deficiency and normalizes cellular metabolism. Over time, it completely biodegrades, leaving no decay products at the injection site.

Indications for use:

• Wrinkles in the perioral and periorbital area
• Dry and dehydrated skin
• Dermal folds
• Thick, atonic skin
• Decreased elasticity and skin tone
• Flabbiness of facial skin
• Atrophic scars, including acne scars
• Flabbiness of the skin of the abdomen and thighs
• Striae

Use in sports nutrition

Riboflavin is a valuable component for those whose activities involve increased physical activity. This is because vitamin B2:

• Participates in protein synthesis.
• Stimulates intercellular oxygen exchange, preventing the development of hypoxia.
• Improves muscle activity during sports.
• Promotes recovery after workouts.

With the systematic use of dietary supplements with vitamin B2, endurance increases and athletic performance improves.

Application in cosmetology

Riboflavin is one of the active substances that are widely used in the beauty industry.

Benefits of Vitamin B2 for Skin

With the help of riboflavin, you can maintain external attractiveness for a long time. Cosmetologists call this substance a “skin” vitamin, thanks to which:

• improves complexion;
• acne disappears;
• seborrhea goes away;
• cracks and ulcers on the lips heal;
• a rejuvenating effect is observed.

The beneficial effects on the skin are due to the fact that riboflavin:

• Exhibits antioxidant properties, inhibiting the negative effects of free radicals.
• Stimulates the formation of energy in cells.
• Helps saturate the skin with oxygen and nutrients.
• Regulates the metabolism of fatty acids.
• Participates in the regeneration and renewal of cells, promoting the healing of damaged tissues.

Cosmetics with vitamin B2 are well suited for problem skin. As a result of their use, inflammatory processes stop and irritation is relieved.

Riboflavin-based creams will help mature women renew their facial skin, restoring its former elasticity and firmness.

To achieve the desired effect, it is not necessary to use finished products. You can prepare an effective vitamin remedy yourself. For this purpose you will need liquid riboflavin (in ampoules).

Revitalizing face mask

Ingredients:

• high-fat kefir - 1 tbsp;
• lemon juice - 15 drops;
• vitamin B2 - ½ tsp.

Combine the ingredients and mix until smooth. Apply the mask in a thick layer to cleansed facial skin and leave for at least 15 minutes. After the time has passed, rinse off the product with cold water.

Benefits of riboflavin for hair and nails

Vitamin B2 has a beneficial effect on the scalp, normalizing the fat balance on its surface. Riboflavin:

• strengthens the hair structure;
• makes them shiny;
• prevents hair loss;
• promotes growth.

Vitamin B2 prevents delamination and brittleness of the nail plate.

For maximum effect, it is recommended to combine the use of cosmetics with the use of riboflavin-based preparations.

Juviderm®

Juviderm® ULTRA 2

An injectable implant designed to fill moderately severe sagging facial skin by injecting the drug into the middle layers of the dermis, as well as to correct the contour of the lips. It is used to eliminate shallow wrinkles, especially at the corners of the eyes and those lying in close proximity to the surface of the skin.

Juviderm® ULTRA 3

An injection implant designed to fill moderate and deep sagging facial skin by injecting the drug into the middle and/or deep layers of the dermis, as well as to increase the volume of the lips and correct their contour. It is most often used to smooth out medium-deep and deep nasolabial folds.

Juviderm® ULTRA 4

An injection implant designed to fill deep sagging facial skin by injecting the drug into the deep layers of the dermis, as well as to increase the volume of lips and cheekbones. Used to fill deep wrinkles using injections, as well as to increase the volume of lips and cheekbones.

Juviderm® ULTRA SMILE

Designed specifically for correcting lip volume and contour.

Juviderm® VOLBELLA™ with Lidocaine

The Juviderm® VOLBELLA™ with Lidocaine intradermal implant is a sterile, pyrogen-free, physiological gel of cross-linked hyaluronic acid using VYCROSS™ technology of non-animal origin. Contains 15 mg/ml hyaluronic acid and 3 mg/ml lidocaine hydrochloride.

Created for:

• plastic surgery of superficial wrinkles and moderately pronounced sagging of the facial skin, which occurs, in particular, with its premature aging;
• increasing the volume of the lips and correcting their contour in order to correct such structural defects as lip asymmetry, unevenness of their contour, loss of lip volume, etc.

Juviderm® HYDRATE™

Sterile, pyrogen-free and physiological solution of hyaluronic acid of non-animal origin. Contains 13.5 mg hyaluronic acid, 9 mg mannitol, phosphate buffer pH 7.2 to a final weight of 1 g.

Designed to increase skin hydration and elasticity by repeated injection of the drug into the area of ​​the dermal-epidermal junction of the skin and the surface layer of the dermis.

Reviews of preparations with vitamin B2

Most consumers who take natural riboflavin supplements report positive changes in their health:

• increased vitality;
• increase in energy potential;
• improvement of brain activity;
• cessation of headaches;
• increased visual acuity, decreased fatigue, redness and tearing of the eyes;
• strengthening the immune system;
• increased hemoglobin;
• reduction of irritability and anxiety;
• improving sleep quality;
• rapid healing of wounds.

After a course of vitamin therapy, women notice pleasant changes in their appearance:

• cleansing the skin from acne;
• improvement of complexion;
• increased turgor;
• strengthening nails;
• stopping hair loss, improving hair growth.

The use of riboflavin in preparations and cosmetics will help maintain health, youth and beauty for a long time.

Meso-Wharton P199™

Meso-Wharton P199™ is the perfect bioreparant and restructuring agent for the 21st century.

An injectable preparation for medical purposes, intended for intensive repair and “rejuvenation” of facial skin after 40 years.

An innovative drug with proven high efficiency, safety and an impeccable reputation, Meso-Wharton P199™ initiates deep, lasting anti-aging and regenerative processes in the skin, which are the result of activating the proliferation and differentiation of the skin’s own stem cells, replacing sluggishly renewed cellular structures of the epidermis and dermis, increasing synthetic fibroblast activity, stimulation of the formation of new collagen.

The Meso-Wharton P199™ injectable drug opens up new possibilities for anti-age therapy - the dream of youth has come true.

Main components:

• "Wharton Jelly Peptide P199"
• hyaluronic acid with a molecular weight of 3300 kDa – 1.5%;
• growth factors (EGF; bFGF; IGF-2);
• thioredoxin (TRX);
• vitamins (A, group B, C, E, K, folic acid);
• amino acids;
• nucleic acids;
• microelements;
• coenzymes.