Various types of burns are among the most common household injuries. There are a huge number of medications available to provide first aid and further therapy. Some of them are created specifically for the treatment of thermal injuries, others have a wider range of applications. For example, Akriderm is not always used for burns, although it is excellent for this. It has also proven itself in the treatment of many other diseases.
Akriderm is a new generation drug intended for external use. It is produced specifically for the treatment of a wide range of skin diseases.
Recently, this medicine has been in high demand among patients. Many of them are interested in what Akriderm helps with. This article is devoted to answering this and other questions.
Pharmacological properties
The medication belongs to the group of hormonal drugs with a wide spectrum of action. The active ingredient is betamethasone. To improve the therapeutic effect and expand the scope of application, the drug contains antifungal and antimicrobial substances, and in rare cases, salicylic acid.
The therapeutic effect is achieved by isolating accumulations of leukocytes and suppressing their action, due to which anti-inflammatory substances are released at the site of the inflammatory process. The effect of the drug is also aimed at reducing swelling, reducing itching and burning sensation in the affected area. At the same time, the process of restoration of damaged tissues is activated.
The popularity of the drug is associated with its complex effect on the epidermis, as well as its high efficiency. The main properties of Akriderm include:
- removal of edema;
- eliminating discomfort in areas of skin damage;
- antiallergic effect;
- antifungal and antibacterial action;
- “dries out” damaged areas;
- promotes rapid tissue regeneration.
The medicine acts immediately after application, penetrating into the tissue through the pores.
Cream and ointment Akriderm
This is the main cream in the line of drugs, with the main active ingredient: betamethasone. Green packaging.
In the photo: Akriderm ointment
Indications for use
- psoriasis (read article about psoriasis)
- acute parapsoriasis
- atopic dermatitis
- allergic dermatitis (popularly simply “from allergies”)
- eczema
- itchy insect bites on the skin
- contact dermatitis (for example, when the skin of the hands comes into contact with construction mixtures)
- bullous dermatoses
- skin itching of various etiologies (that is, various causes)
- discoid lupus erythematosus
- lichen planus
- exudative multimorphic erythema
Instructions for use
- Apply Akriderm cream or ointment to the affected area of skin in a thin layer 1-2 times a day, lightly rubbing. You don’t have to rub the cream in – it is absorbed on its own.
- The course of treatment is 3-4 weeks. After this, treatment should be stopped and further actions should be coordinated with a dermatologist. Attention : doctors are against daily use of Akriderm for more than 1 month.
- Apply on the face no more than 5-7 days in a row to avoid side effects. A preliminary consultation with a dermatologist is required!
- On the genitals (penis, labia) lubricate carefully, also for no more than 5 days. A preliminary consultation with a dermatologist is required!
- If it is necessary to continue the course of treatment, then in the future the regimen of using the cream should be intermittent - every 1-2 days.
Can pregnant women apply Akriderm?
It is forbidden!
Is it possible for nursing mothers?
It is possible, but breastfeeding should be stopped for the entire course of lubricating the skin with this drug.
Can it be applied to children?
Possible, only from 1 year. For a very short period of time (2-3 days maximum) and only on a limited area of the body, so that the drug is not absorbed into the child’s body.
Side effects
May appear only with prolonged use.
- skin itching and burning, skin irritation,
- pustules, pimples and blackheads on the skin,
- lightening of the skin in a limited area (hypopigmentation),
- excess hair growth (hypertrichosis),
- stretch marks (pregnant stretch marks),
- dermatitis around the mouth,
- skin atrophy.
Contraindications
- lupus,
- syphilis on the skin,
- chicken pox (chickenpox),
- herpes. If you have herpes, you can't!
- skin reactions after vaccinations,
- open wounds,
- trophic ulcers,
- rosacea,
- pustules and acne,
- skin tumors - nevus, atheroma, melanoma, hemangioma, xanthoma, sarcoma,
- lactation period,
- children under 1 year.
Release form
instructions for use
The drug is produced in three dosage forms:
- ointment is a viscous substance of white or slightly yellowish color, possibly with a slight specific odor. One gram of the medicine contains sixty-four hundredths of a gram of active substance, as well as auxiliary ingredients.
- Cream and gel are a white, odorless substance. The ratio of medicinal components is the same as that of the ointment.
The medicine is packaged in aluminum tubes of fifteen or thirty grams each. The shelf life is three years from the date of production.
Comparison of the effectiveness of Akriderm GK and Akriderm genta
The effectiveness of Akriderm GC is quite similar to Akriderm genta - this means that the ability of the medicinal substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Akriderm GC is more pronounced, then using Akriderm genta even in large doses will not achieve this effect.
Also, the speed of therapy is an indicator of the speed of the therapeutic action; Akriderm GK and Akriderm gents are approximately the same. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Indications for use
instructions for use
As already mentioned, there is an extensive list of diseases for the treatment of which Akriderm can be used. These are not only all kinds of skin diseases, but also burns, as well as autoimmune pathologies. Most often this medicine is used to treat the following ailments:
- dermatitis;
- skin itching;
- eczema;
- psoriasis;
- lichen simplex;
- acne;
- chickenpox;
- haemorrhoids;
- first and second degree burns;
- fungus;
- insect bites;
- Diaper rash.
Since the drug Akriderm is a hormonal steroid drug, its use is allowed only after consultation with a dermatologist.
ACRIDERM® PREPARATIONS FOR THE TREATMENT OF VARIOUS TYPES OF DERMATOSES
1. Instructions for medical use of Akriderm® GK.
2. According to the independent retail audit company of pharmacies IQVIA, among topical steroids containing a combination of “hormone + antibiotic + antifungal agent”, calculated per 1 g for the period January-March 2022
3. Efficacy and tolerability of the Akriderm® “line” in the practice of a dermatovenerologist, Matushevskaya E.V., Shakurov I.G., Khismatullina Z.R., Klin. derm. and Venerol., 2008, No. 2, pp. 12-17
— Efficacy and safety of using Akriderm® GK cream in children with allergic dermatitis, Liang N.A., Kornacheva L.A., Cheburkin A.A.,
— Experience in the use of Akriderm® drugs in complex therapy of patients with chronic dermatoses, Chigodaykin G.P., Kovaleva Zh.V., Neminushchiy Yu.G., Beketov A.M., Current issues of dermatovenerology: materials of the XVI regional scientific and practical conference dedicated to 110th anniversary of Professor Gitelzon I.I., Krasnoyarsk, 2006, pp. 134-135
— Clinical and immunological parameters in patients with atopic dermatitis during treatment with Akriderm® line drugs, Ertneeva I.Ya., Matushevskaya E.V., Svirshchevskaya E.V., Clinical dermatology and venereology, 2008, No. 5, pp. 35-39
4. Glucocorticosteroids for local use in a modern strategy for the treatment of inflammatory dermatoses in pediatric practice. Batyrshina S.V. 09 (14) Practical Medicine. 2014: 30-35
5. Patent No. 2223097, Patent No. 2325912
6. Topical hormonal drugs are the first choice drugs for the treatment of dermatitis. Federal clinical guidelines for the management of patients with atopic dermatitis and eczema. 2015
7. Redness, itching, inflammation, infection in the following diseases: simple and allergic dermatitis (especially complicated by secondary infection), diffuse neurodermatitis (including atopic dermatitis), limited neurodermatitis (including simple chronic lichen), eczema , ringworm (dermatophytosis, candidiasis, lichen versicolor). According to the instructions of Akriderm GK
8. Instructions for medical use Akriderm®
9. Khardikova S.A. Rational choice of a combined topical glucocorticosteroid in an outpatient appointment with a dermatovenerologist // Clinical dermatology and venereology, 2018. No. 2. pp. 67-72.
10. Simple and allergic dermatitis (especially complicated by secondary infection), diffuse neurodermatitis (including atopic dermatitis), limited neurodermatitis (including simple chronic lichen), eczema, dermatomycosis (dermatophytosis, candidiasis, lichen versicolor), especially when localized in the groin area and large folds of skin.
Use for burns
It is recommended to use the drug only in the treatment of minor first and second degree burns. They look like this:
- A first degree burn results in minor redness and swelling of the skin.
- The second degree is characterized by a larger area of damage. Blisters containing a cloudy liquid appear on the reddened skin. After their breakthrough, a bright red wound surface is released.
Treatment of more serious thermal injuries with this drug is not effective.
Instructions for treating burns:
- Before treating the damaged area with the medicine, it must be thoroughly rinsed with warm water.
- The medicine is applied to the affected areas in a thin layer. It needs to be rubbed a little into the underlying tissue. The procedure is carried out up to three times a day.
- Applying a bandage is strictly prohibited.
- The duration of treatment depends on the severity of the burn and the individual characteristics of the patient. Usually it is about two weeks. If there are no visible improvements, you should contact your doctor to adjust the treatment.
- If you notice the first symptoms of an allergic reaction, you must immediately stop using the drug.
Various side effects may occur when using this medication. In this case, your doctor will prescribe an alternative course of treatment.
Composition of the drug
The uniqueness of the drug lies in three active substances:
- Betamethasone dipropionate. It penetrates deeply into the site of inflammation, has high hydrophobicity, provides a rapid therapeutic effect and long-lasting action. One tube of cream contains 0.064 g of betamethasone dipropionate.
- Gentamicine. This substance is a broad-spectrum antibiotic from the aminoglycoside group. Provides a bactericidal effect against many gram-positive and gram-negative microorganisms. Akriderm GK cream contains 0.1 g of gentamicin sulfate.
- Clotrimazole. It has a pronounced antifungal effect. The drug contains 1 g of clotrimazole.
Thanks to the combined composition, the drug not only relieves itching, redness and inflammation, but also helps eliminate pathogenic microorganisms. The active substances present in the cream complement and enhance each other’s actions, which will allow for more successful treatment of both subjective and objective symptoms of the disease.
Due to the higher concentration of water, the product is absorbed faster and is suitable for wet and thin areas of the skin. Also suitable for use on lesions localized in large folds of the skin.
In addition to purified water, the auxiliary components of the Akriderm GK preparation are:
- petrolatum;
- propylene glycol;
- liquid paraffin;
- cetostearyl alcohol;
- macrogol cetostearate;
- disodium edetate;
- sodium dihydrogen phosphate dihydrate.
Contraindications
Like all hormonal drugs, Akriderm has contraindications for use, the list of which is quite extensive. The drug should not be used in the following cases:
- in case of individual intolerance to one or more components of the drug;
- hypersensitivity to the drug;
- lupus;
- syphilis;
- herpes;
- ulcerative damage to the skin;
- acne;
- during pregnancy and breastfeeding;
- Do not treat bleeding wounds;
- cannot be used to treat children under one year of age;
- for glaucoma;
- for hyperglycemia, since the drug significantly increases blood sugar levels.
Do not use the medication to treat facial skin for more than five days. This can lead to undesirable consequences, such as hypertrichosis and increased pigmentation of the skin.
pharmachologic effect
The drug "Akriderm GK" has a versatile effect:
- anti-inflammatory;
- antiallergic;
- antibacterial;
- antifungal (fungicidal).
This effect was achieved largely thanks to betamethasone. This component is a glucocorticosteroid and has a local anti-inflammatory, anti-edematous, anti-allergic effect.
In turn, gentamicin has a bactericidal effect. It even suppresses microorganisms that are resistant to other antibiotics.
The main function of clotrimazole is to prevent the activation of fungal flora against the background of the action of gentamicin. This component is an antifungal agent from the group of imidazole derivatives for topical use. It has an effect by disrupting the synthesis of ergosterol, which is an integral part of the cell membrane of fungi. Clotrimazole is also active against pathogenic dermatophytes, yeast and mold fungi.
Side effects
In case of overdose or improper use of the drug, side effects may occur:
- dryness and flaking of the skin;
- atrophy of the skin on the treated area;
- facial skin pigmentation may increase;
- disruption of the adrenal glands;
- prickly heat;
- excessive development of hair at the burn site;
- increase in total intracranial pressure;
- skin irritation;
- a noticeable increase in blood sugar (hyperglycemia);
- manifestation of symptoms from the cardiovascular system;
- hearing impairment.
The first thing to do if any of the listed symptoms appear is to stop using the drug.
Comparison of ease of use of Akriderm GK and Akriderm genta
This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.
The ease of use of Akriderm GK is approximately the same as Akriderm genta. However, they are not convenient enough to use.
The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.
Last update date: 2020-12-04 13:45:10
Analogs
Today Akriderm is widespread in our country. It can be bought at almost every pharmacy. The cost of the medicine depends on the volume of the package. Depending on the region, it ranges from one hundred to six hundred rubles per package. This medicine has many domestic and foreign analogues, which can be used on the recommendation of your doctor if you have problems with Akriderm. Some of them are noticeably cheaper than the drug described.
The most commonly used analogues are:
- Advantan;
- Momoderm;
- Triderm;
- Darmadrin;
- Kanizon Plus;
- Triacutan.
All these drugs are designed specifically for the treatment of various injuries and diseases of the skin, including thermal burns. Some of them will help to cope even with third and fourth degree burns, which Akriderm cannot do.
Benefits of Akriderm GK cream
First of all, it is worth noting the affordable price of the drug. "Akriderm GK" is available in packages of 15 g and 30 g. The price of a 30 g tube is more favorable for the buyer compared to 15 g of another product against skin problems. The drug also has over-the-counter status and is available to a wide range of consumers.
But the main advantage of Akriderm GK lies in its versatile action. It deals a powerful blow to the source of inflammation, affecting not only the external manifestations of the disease, but also its causes. Many patients have reported a significant reduction in itching, redness and swelling after application.
