Retinoids for acne - preparations for the skin and internally: list, names, reviews. Rules for taking retinoids for the treatment of acne and psoriasis

Retinoids are included in various modern acne treatments. These are effective drugs, ointments, creams, gels and lotions.

For the comprehensive treatment of skin diseases, dermatologists prescribe effective medications with retinoids. All girls and women dream of being beautiful. Various skin rashes spoil the appearance and force women to purchase products that really help cope with acne and other skin diseases.

• This group of substances gets its name from the word “retinol”. In medicine this is the name of vitamin A.
• This substance is involved in the differentiation of the upper layer of skin. At first, retinol was used in its pure form, but its effect caused the skin to peel and become dry. Scientists made a change in the structure of the substance and introduced it into preparations. The toxic effects on the epithelium were reduced, and the drugs turned out to be effective.
• Nowadays, retinoids are included in many drugs for healthy hair, skin, acne treatment and even cellulite prevention.

Systemic and topical retinoids: what are they and how do they act on the skin?

Systemic and topical retinoids: what are they and how do they act on the skin?
The skin has receptors that are sensitive to retinoic acid. When retinol enters skin cells, they receive a signal to form special molecules that have a beneficial effect on synthesis.

• Retinoids do an excellent job with the growth of epithelial cells and inhibit this process.
• Thanks to this effect of vitamin A in skin cells, new ducts of the sebaceous glands do not appear , which reduces the inflammatory process and increases the activity of immune system cells.
• In such conditions, bacteria cannot multiply , acne disappears, and the skin becomes soft and elastic.

What are systemic and topical retinoids and how do they work on the skin?

• Systemic retinoids are tablets that need to be taken systemically. Tablets are prescribed in specific daily doses. They must be taken for 3-4 months or even more. Thanks to such drugs, the secretion of the sebaceous glands is reduced within a month after using the tablets. After discontinuation of the drug, secretion remains reduced for up to six months, and then returns to its original values.
• Topical retinoids are medications that are used to treat the skin externally. Creams, gels, lotions help the skin recover completely and get rid of acne.

In the treatment of acne and other diseases of the upper layer of the epithelium, it is important to follow the doctor’s recommendations regarding the prescribed medications, as well as perform maintenance therapy for a long period of time after treatment.

Pimples* on the cheeks: causes

If small pimples* appear on the face from time to time, but in general the skin is not problematic, it is enough to get rid of several “bad” habits:

• clean makeup brushes;
• stop touching your face with your hands;
• Use a regular face towel instead of a disposable paper one.

The causes of deeper acne*, widespread throughout the face or body, which does not go away for a long time, can be4,50:

• unbalanced diet;
• bad habits;
• genetic predisposition;
• hormonal disorders;
• problems with the gastrointestinal tract;
• stress;
• incorrectly selected skin care products.

The exact cause of acne can only be determined after undergoing diagnostic tests at a dermatologist's office.

Retinoids: contraindications

Retinoids: contraindications
Despite the fact that retinol is a vitamin that the skin needs to keep it healthy and beautiful, there are contraindications for its use. Women who are preparing to become mothers should be careful. Retinoids in any form should not be used during pregnancy as they may cause developmental defects in the fetus.

Other contraindications for taking retinoids:

• breastfeeding period;
• increased skin sensitivity;
• liver diseases;
• drinking alcohol and smoking.

Important: Before starting to use retinoids, consult your doctor!

Systemic retinoids for acne

For severe forms of acne, which include cystic acne and conglobate acne, the use of topical retinoids for the face is ineffective. In these cases, systemic drugs are prescribed, which include Roaccutane, Sortret, Acnecutane and Verocutane. The main active ingredient of these drugs is isotretinoin.

The dosage of systemic retinoids is selected based on individual characteristics: age, body weight, severity of acne.

Oral preparations based on isotretinoin have many side effects and contraindications, and therefore should be prescribed exclusively by a doctor and used under his supervision to avoid complications.

Rules for taking retinoid tablets orally for the treatment of acne and psoriasis

Rules for taking retinoids in tablets orally for the treatment of acne and psoriasis
Any chemical preparations have a certain dose of toxicity. Therefore, they must be taken as prescribed by a doctor. There are rules for taking retinoid tablets orally to treat acne and psoriasis. These include the following:

• Usually treatment lasts at least 4 months.
• If necessary, a second course is carried out. The doctor prescribes it. Self-medication can lead to undesirable health consequences.
• It is necessary to constantly monitor the functioning of the liver.
• The patient must study the side effects, and the doctor must determine the balance of benefits and risks from the use of such drugs.
• After taking a course of retinoids, it is necessary to carry out maintenance therapy, which will help the skin cells to finally recover and improve their health.

Many medications must be taken with food, as they are better absorbed with fat. Your doctor will be able to tell you about all the nuances of taking each acne medication.

How to Increase the Effectiveness of Retinoids

During acne treatment, it is very important to ensure proper and regular skin care. To increase the effectiveness of topical retinoids, medicated acne wash gels are used.

Proper nutrition also plays an important role in acne. From the diet of those suffering from acne, it is recommended to completely exclude or minimize the consumption of fatty, sweet, fried and smoked foods, that is, those foods that contain a large number of carcinogens. Food of plant origin must be included in the daily menu. All types of fresh vegetables, fruits and berries are very beneficial for the skin. Fish, meat, nuts, whole grains and dairy products are also necessary for healthy skin.

Retinoids for acne: list of drugs with names

Retinoids for acne: a list of drugs with names
Retinoic acid is a component that is used in preparations for both external and internal use. Such products help not only get rid of acne, but also eliminate scars and facilitate the cleansing of the ducts of the sebaceous glands.

What retinoids are there for acne? List of drugs with names:

• Roaccutane (isotretinoin) - capsules for oral use. The number of acne is reduced due to the slowdown in the formation of comedones, as well as due to the excellent anti-inflammatory effect.
• A solution of retinol palmitate (vitamin A) in oil 100,000 IU/ml - the process of sebum secretion is reduced. It is absorbed in its pure form, unlike the cheaper analogue of retinol acetate.
• Retinoic ointment is a safe drug without side effects.
• Retasol is a solution for external use.
• Differin is a drug for external use. Apply to the affected areas of the epithelium.
• Tazarotene is an acne cream, used once a day for 3 months.

There are many other drugs with retinoids that do an excellent job of treating skin diseases. Your attending physician will help you choose the right remedy and treatment regimen.

How can you cure acne?

Acne treatment is a long process that must be carried out under the supervision of a specialist. Acne must be treated with medications prescribed by a dermatologist. For mild to moderate acne, the doctor may prescribe topical antibiotics, for example, Clindovit® gel6,18. The drug must be used 2-3 times a day6. The drug contains clindamycin phosphate, which is hydrolyzed to form clindamycin, a lincosamide antibiotic6.

Clindovit® gel is recommended to be combined with benzoyl peroxide or azelaic acid (for example, Azelik® gel) in order to reduce the risk of developing antibiotic resistance28.

*acne

Retinoids and peptides in anti-wrinkle cosmetics

Retinoids and peptides in anti-wrinkle cosmetics
Peptides and retinoids are components that are used in the production of anti-aging cosmetics. The advantages of these substances when used externally are that they are suitable for almost everyone. They have little toxicity, are not allergenic, do not cause adverse reactions and perfectly improve the condition of the skin.

Corporations around the world use retinoids and peptides in the production of anti-wrinkle cosmetics. Cosmetologists advise using such drugs in courses. Creams should be applied 2 times a day at the initial stage of skin treatment. In the future, after obtaining a noticeable effect, the frequency of use is reduced to 2 times a week.

BeautyVitamin A: 12 effective products with retinol

Text: Mur Soboleva, author of the Fierce&Cute telegram channel

Retinol is called the only working component for mature skin, and in some cases it is also effective in preventing acne. We have already talked about the power of vitamin A and its derivatives - and now we have chosen different products with this component. We remind you that it is better to introduce any products with retinoids into your care gradually, starting with a minimal regimen: some cosmetologists recommend starting with one use per week and working up to daily use, others suggest using retinol every other day. Monitor the condition of your skin and, if necessary, consult a specialist.

Night cream SkinCeuticals Retinol 0.3

5682 rub.

SkinCeuticals has several retinoic products in different concentrations, but only this night cream with 0.3% retinol is available on the Russian market - it is quite mild, and the brand recommends the product for beginners in the world of vitamin A derivatives. The formula contains many emollient components, from hyaluronic acid before oils, it is declared as non-comedogenic and stable.

Verso 123 Travel Series Set

5300 rub.

The Swedish brand Verso does not indicate the percentage of retinol content in its products, putting the inscription “Retinol 8” on the packaging: the brand has patented a formula that, according to the results of their internal research, is eight times more effective than “classic” retinol. The creator of the brand, Lars Fredriksson, says that the point of the formula is a fairly low content of retinoids, well balanced with other active ingredients, such as niacinamide.

Skincare Cosmetics Retinol-X Anti-Aging Eye Lift Eye Cream

2890 rub.

The American brand Skincare Cosmetics, under the name Retinol, produces a whole line of products - from cleansing gel to masks. The brand is a little disingenuous in its notation: instead of the accepted percentage, it indicates the amount of retinol palmitate in IU (international units of measurement), which, even with a chemical education, is difficult to convert into percentages without knowing all the inputs. However, Paula Begun states that there is no direct correlation between the amount of retinol and its effectiveness and it is not necessary to look for the highest concentration on the market. The main thing is that the products work honestly and at the same time gently.

Local action stick Académie Purifying Concentrate

1790 rub.

Typically, products with retinol are labeled “anti-aging” or “anti-wrinkle,” but vitamin A derivatives are often used to normalize the functioning of the sebaceous glands (and for severe forms of acne, doctors prescribe specific forms of retinoids for oral administration). At Académie, retinyl palmitate is used for this very purpose - in this local treatment it works against inflammation and acne in combination with zinc and iris extract.

Night face gel Rejudicare Retinol SRX

4190 rub.

Canadian brand Rejudicare works with known active ingredients and does it very well—the brand is especially fond of vitamin C and retinoids. The line of the latter consists of three night gels with different concentrations of retinol: SRX Mild with a minimum percentage (0.15%), medium SRX with a concentration of 0.35% and maximum SRX Max. The classic “retinol ladder” involves gradually increasing concentration: start with the mildest product and then move on to more serious ones.

La Roche-Posay Redermic R face cream and Redermic R Yeux eye cream

2156 rub. and 1904 rub.

The Redermic line is divided into Redermic C with vitamin C in different concentrations (depending on the number next to the letter C) and Redermic R - with two types of retinol, respectively. There is little pure retinol in the products - 0.1%, but here it is combined with another retinoic compound, retinol linoleate. These are gentle and neat products with good enriched ingredients: for example, Redermic R Yeux contains draining caffeine, and Redermic R contains hyaluronic acid.

Peter Thomas Roth Retinol Fusion PM Overnight Resurfacing Pads

5300 rub.

A good American brand is distributed in its homeland by Sephora, and the brand was brought to Russia by the Cosmotheca store. Peter Thomas Roth, as befits a cosmetics mogul these days, only works with trendy ingredients and balances them well. In the line with retinol, the most interesting product is exfoliating discs without acids and alcohol: glucosamine and vitamin C are responsible for exfoliation, and a whole bunch of moisturizing components are added to prevent the skin from drying out.

Methode Cholley Bioforce Crème Raffermissante face cream

8460 rub.

The niche Swiss brand mainly produces salon products for luxurious treatments in luxurious interiors. For the same reasons of reliability, the brand has created a separate men's line, Bioforce. But nothing prevents women from using it: as a rule, “male” products have a lighter texture and a more matte finish, but otherwise gender differences do not appear in any way. And this cream also has a good composition: there is little retinol, and it is accompanied by vitamin C and peptides.

Phyto-C Skin Care Retinol Serum 1%

5390 rub.

The Phyto-C Skin Care brand was created by Dr. Mustafa Omar, a man who at various times worked at SkinCeuticals and iS Clinical - he is credited with the world's first stabilized form of vitamin C in cosmetics. In Phyto-C, the retinoic serum has a very simple formula - it contains only water, anhydrous alcohol and retinol itself. This is pure hardcore: the product is effective, but only for advanced users; you definitely shouldn’t start with vitamin A.

Ultraceuticals Ultra A Skin Perfecting Serum Mild

about 7000 rub. in clinics and beauty salons

A strong Australian brand stabilizes retinol using microencapsulation technology - this way the component is better stored and penetrates better into the skin. Ultraceuticals is very careful with active products and recommends starting with the mildest concentrations (in the case of retinoids, this is Ultra A Skin Perfecting Serum Mild), introducing gradually, and when moving to more serious concentrations, consult a doctor.

Medicalia Skincare Retinol Concentrate

3240 rub.

The American dermatological brand Medicalia Skincare makes products with beta-carotene (a precursor of vitamin A), and this concentrate also contains microretinol - as the brand claims, this way the initially unstable component penetrates the skin better. It is difficult to balance vitamin C with retinol, but Medicalia did it - it contains both it and hyaluronic acid.

Photos: SkinCeuticals, Cosmotheca (1, 2), Il de Beaute, Academie, Skinguru, La Roche-Posay (1, 2), Methode Cholley, Pudra, Ultraceuticals, Medicalia Skin Care

Retinoids: reviews

Retinoids: reviews
Every girl wants to have beautiful skin, because an attractive appearance indicates good health. With clean skin, a woman feels confident in any situation. To help their patients get rid of acne quickly and effectively, doctors prescribe retinoids. Reviews from different people who have recovered from skin diseases:

Ekaterina, 26 years old

I had a mild form of acne. As the doctor said at the beginning of treatment, my mixed form of acne is comedonal papulopustular, and can be treated well with retinoids. The doctor prescribed me a drug for internal use. Liver parameters were also monitored. The treatment lasted 3 months. Now my facial skin is clean and beautiful.

Valery. 23 years old

Skin problems started at age 15. First acne appeared on the forehead, then on the cheeks. I contacted a dermatovenerologist. The doctor prescribed treatment with retinoids. I took 70 mg per day for a long time. Then the dose was reduced. The drug was well tolerated and was tested regularly. A year has already passed since the treatment and my skin is clear.

Yulia, 18 years old

I have problem skin. I realized this at the age of 15, when acne began to appear one after another. I tried all the advice from my friends, applied all sorts of creams and lotions - nothing helped. Then my mother took me to a cosmetology clinic to see a dermatologist. The treatment lasted 3 months. I liked how the appearance of my skin and face in general changed. Now the skin is beautiful and clean. To prevent acne from appearing again, the doctor prescribed a special cream.

Properties and types of vitamin A

Vitamin A is a term that refers to several substances - retinol, tretinoin and its derivatives (retinoids), as well as beta-carotene and some other carotenoids. Vitamin A, together with vitamins D, E, K, belongs to the fat-soluble group.

Retinoids are actively used in the treatment of dermatological diseases - acne, rosacea (red pimples* on the cheeks) - due to their properties, they have the following effects132:

• improves exfoliation of the stratum corneum of the epidermis;
• promotes healing of inflamed acne*;
• reduces sebum secretion;
• reduces the colonization of bacteria responsible for the appearance of acne on the face (usually on the forehead, cheekbones and cheeks)*.

Only a dermatologist can justify which form and why will be most effective for the patient.

What are retinoids and who are they indicated for?

Retinoids are natural or synthetic derivatives of vitamin A - retinol, the deficiency of which in the body leads to deterioration of cell regeneration. The skin suffers especially from its lack; a common consequence is the appearance of pimples and acne. The following properties of retinoids are successfully used for their therapy:

• significant limitation of fat secretion production;
• increasing local immunity;
• rapid exfoliation of dead epithelial cells;
• reducing inflammation by suppressing the growth of new sebaceous gland cells;
• increasing the firmness and elasticity of the skin.

Retinoids help against pimples, acne, acne, as they act on the cause (incorrectly working sebaceous glands), eliminating the consequence - various rashes.