Comparing Akriderm and Akriderm GK | Determining the best

Updated: 04/23/2021 15:11:06

Expert: Abramova Tsilya

Akriderm is an ointment for topical use based on betamethasone. Akriderm GK is a drug with an additional composition and a wider range of applications. We analyzed both ointments to understand in which cases it is better to give preference to one or the other.

Description of Akriderm and Akriderm GK

Akriderm hormonal ointment is based on betamethasone. This is a potent remedy that must be used according to indications. It is usually prescribed when non-hormonal ointments do not provide the desired result. Manufacturer: Akrikhin, Russian Federation.

Betamethasone is a glucocorticosteroid substance that can inhibit the release of inflammatory mediators. The pronounced effect of the drug allows it to be used to quickly eliminate dermatological manifestations such as swelling, itching, redness in severe diseases.

Akriderm GK contains not only betamethasone, but the following substances:

1. gentamicin – antibacterial agent;
2. Clotrimazole is an antifungal agent.

Pharmacodynamics and pharmacokinetics

This drug is topical glucocorticosteroid Its main substance, betamethasone dipropionate, can inhibit the accumulation of leukocytes , the process of releasing lysosomal enzymes , as well as anti-inflammatory mediators at the site of inflammation. In addition, phagocytosis is inhibited, vascular-tissue permeability is reduced, preventing the occurrence of inflammatory swelling.

Research and effectiveness

Before determining the causative agent of the disease, combination drugs with a wide spectrum of antibacterial action are prescribed. These include Akriderm GK. It may be the drug of choice, as it is active against common bacterial and fungal pathogens.

Research results show a good therapeutic effect of the ointment in the treatment of dermatoses, chronic inflammatory diseases, and fungal-bacterial infections. Using the product gives a quick anti-inflammatory effect. Due to its effectiveness and relative safety, it is recommended for dermatoses of various origins. The use of the drug provides a high level of bacterial cure.

Source

to: Kasikhina E.I., Glazko I.I. “Problems of mixed infection: solutions and features of pathogenesis,” 2014.

Instructions for use Akriderm (Method and dosage)

Akriderm ointment, the instructions for use of which recommend applying it to the affected surface of the skin, is used twice daily. A different therapeutic regimen may also be prescribed, taking into account the severity of the disease.

When treating mild cases, Akriderm cream, instructions for use, allows for application once, and for more severe lesions - up to several times a day.

The duration of treatment may depend on various factors: the effectiveness and tolerability of the drug, the severity of the disease and the characteristics of the patient’s body. On average, the therapeutic course is 2-4 weeks.

When improvement does not occur for a long time, urgent clarification of the diagnosis is necessary.

Contraindications

Each glucocorticosteroid drug has strict restrictions on its use. Akriderm is not prescribed until one year of age or during pregnancy. When it is necessary to treat a child, the ointment can only be used under the supervision of a doctor.

Betamethasone can disrupt hormonal levels, so the ointment is used with caution in childhood and during lactation.

Other contraindications for use:

1. viral skin diseases;
2. benign and malignant neoplasms;
3. open wounds;
4. perioral dermatitis;
5. lupus;
6. post-vaccination reactions;
7. intolerance to components and allergies to them.

Side effects

Corticosteroid ointment can provoke systemic reactions, since when applied topically, a certain amount enters the bloodstream. If any unpleasant symptoms appear, you should immediately visit a doctor for symptomatic treatment and choose another medicine.

Possible side effects from using the ointment:

1. allergies – itching, dry skin, irritation;
2. rash, urticaria;
3. prickly heat;
4. folliculitis;
5. atrophic processes of the skin;
6. maceration;
7. hyperglycemia;
8. hypertrichosis;
9. swelling;
10. osteoporosis;
11. increased blood pressure.

Akriderm price, where to buy

The price of Akriderm ointment is from 85 rubles.

The price of Akriderm cream varies between 100-300 rubles.

You can buy any form in any Russian pharmacy, as well as outside the country.

For example, the price in Ukraine is 80-385 UAH depending on the volume of packaging.

• Online pharmacies in RussiaRussia
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Akriderm Genta ointment 0.05%+0.1% 30g JSC Akrikhin
  RUB 381 order
• Akriderm Genta ointment 0.05%+0.1% 15gAO Akrikhin

  RUB 263 order

• Akriderm GK ointment d/nar. approx. 0.05%+0.1%+1% 15gJSC Akrikhin

  RUR 484 order

• Akriderm GK cream 30gAO Akrikhin

  RUR 783 order

• Akriderm cream 0.05% 30g JSC Akrikhin

  RUB 159 order

Pharmacy Dialogue

• Akriderm GENTA ointment (tube 15g) Akrikhin OJSC

  RUB 245 order

• Akriderm SK ointment (tube 30g) Akrikhin JSC

  RUB 443 order

• Akriderm SK ointment (tube 15g) Akrikhin OJSC

  RUB 272 order

• Akriderm GENTA cream (tube 15g) Akrikhin OJSC

  RUB 242 order

• Akriderm cream (tube 0.05% 15g) Akrikhin JSC

  84 rub. order

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Dosage

The ointment is applied to the skin in a thin layer 2 times a day. The frequency of use may be changed by the doctor depending on the course of the disease. Do not allow the product to come into contact with the eyes. The course of treatment usually lasts up to 4 weeks. Treatment for more than a month may lead to an overdose. If there is no effect of use, you should consult a dermatologist.

For acne

For acne, HA may be prescribed. Its use allows you to quickly get rid of skin problems. For dry skin types, ointment is used, for oily skin types, cream is used. The drug is effective for purulent rashes. It can be used for the face for no longer than 5 days, for the body - up to 2 weeks. The ointment is applied pointwise to the rash with a sterile cotton swab.

From deprivation

GK ointment can be used for lichen. It is effective because it copes well with itching, inflammation and swelling of the skin. It also fights fungus and bacteria. In this case, regular Akriderm ointment will help prevent skin thickening. The course of use of the product is about 2 weeks, after which you need to undergo a re-examination by a doctor.

For allergies

For allergic diseases, corticosteroid ointment may be prescribed when other local remedies are ineffective. If allergies are complicated by bacterial skin lesions, Akriderm GK or SK should be used.

Akriderm medications themselves can also cause allergies. Treatment is permissible only as prescribed by a doctor. If after the first application, the symptoms intensify, you need to abandon this medicine and choose an analogue together with your doctor.

From fungus

Due to the content of the antifungal agent clotrimazole, Akriderm GK can be used for fungal skin infections. It is used for 14-30 days, 2 times a day.

For eczema

For eczema, all types of ointments can be used. The most effective treatment option is medicated bandages. The drug is applied 2 times for 40-50 minutes. The course is standard – up to 3 weeks.

Treatment can lead to dry skin, so it is recommended to use a natural moisturizing cream in parallel.

The difference between ointment and cream

Dosage forms of Akriderm have exactly the same qualitative and quantitative composition of the active ingredient. They vary significantly in the content of the components that were used by manufacturers to form the base. The patient should not choose whether to use Akriderm ointment or cream for treatment. It all depends on the doctor, who takes into account the results of laboratory tests and takes into account possible risks. What are the main differences between the two dosage forms:

• auxiliary ingredients of the ointment ensure optimal transepidermal penetration of the active substance into the tissue;
• the ingredients for forming the cream base have therapeutic properties and alleviate the severity of symptoms.

The cream is easily absorbed and distributed in tissues damaged by the inflammatory process. And the ointment also has a preventive effect. After its application, a greasy film is formed on the skin, preventing the penetration of pathogenic microorganisms into ulcers and wounds.

Rules for choosing a dosage form

Dermatologists prefer to use Akriderm cream for acute skin inflammation of various locations. This dosage form has a softening and moisturizing effect. The cream cools the skin and helps reduce the severity of clinical manifestations:

• itching and burning;
• swelling and redness;
• painful sensations.

The ointment is used most often in the treatment of chronic skin pathologies. The glucocorticosteroid penetrates into the deepest layers of the epidermis, stopping inflammation and preventing its spread. The ointment ensures maximum and long-lasting therapeutic effects on damaged tissues.

The Akriderm therapeutic line is represented by four products that differ in the content of glucocorticosteroids and other active components. Here, for example, is the difference between Akriderm and Akriderm GK:

• concentration of active ingredients, significantly higher in Akriderm GK;
• the presence in Akriderm GK of the antimycotic clotrimazole and the antibiotic gentamicin.

All varieties of the drug also have two dosage forms - cream and ointment. Which drug is suitable individually for the patient depends on the type of inflammation of the skin.

Who is it suitable for?

Akriderm has anti-inflammatory, decongestant, antiexudative, antihistamine effects. This allows it to be used for various skin lesions when more gentle drugs do not have an effect.

Main indications for the use of different types of ointment:

Akriderm GK is a combined local remedy containing an antibiotic and an antifungal agent. This leads to wider application.

Indications for use

During the use of Akriderm GK cream, a positive therapeutic effect is observed in relation to acute and subacute conditions. The drug has average penetrating ability and has a softening and cooling effect on the source of inflammation. Also used to combat diseases such as:

• simple and allergic dermatitis, especially complicated by secondary infection;
• diffuse neurodermatitis, including atopic dermatitis;
• limited neurodermatitis, including simple chronic lichen;
• eczema;
• dermatomycosis (dermatophytosis, candidiasis, lichen versicolor), especially when localized in the groin area.

The unique composition places the drug "Akriderm GK" in the most popular group of products that provide significant improvement after use.

Cost and analogues

The following products are analogues of Akriderm:

1. Beloderm is a local remedy based on betamethasone, acts strongly and quickly directly at the site of the inflammatory process, reduces external manifestations and subjective sensations such as pain, irritation, itching, and constant discomfort;
2. Diprospan is a drug in a solution based on betamethasone, which is prescribed in severe cases to relieve symptoms during the acute period of the disease;
3. Celestoderm-B is a betamethasone-based cream used for skin diseases with a secondary infection.

As an alternative to these drugs, the doctor may prescribe analogues of action, but with other active ingredients. Popular products include Triderm, Betaderm, Celeston, Diprosalik, Candid-B, Kanzinon.

Composition and release form

The Akrikhin pharmaceutical factory produces cream and ointment in aluminum tubes, packaged in 15.0 g and 30.0 g. If the product is intended for long-term treatment, then it is advisable to purchase a large package. This way it is possible to save about a third of the cost of the anti-inflammatory drug. Its average price in pharmacies:

• ointment 15 g - 96 rubles;
• ointment 30 g - 125 rubles;
• cream 15 g - 122 rubles;
• cream 30 g - 160 rubles.

Secondary packaging of medicines is a cardboard box with a detailed annotation attached. The cream and ointment contain an identical concentration of glucocorticosteroid. Only the composition of the ingredients used by the manufacturer to structure the base differs:

• ointment - paraffin, propylene glycol, distilled water, petroleum jelly, wax;
• cream - methylparaben, petroleum jelly, propylene glycol, organic alcohol, stabilizers.

Some auxiliary ingredients of the ointment and cream have antiseptic properties and sanitize inflammatory foci. They enhance and prolong the effect of the active ingredient due to the gradual complete absorption of the glucocorticosteroid.

Which drug is better

Classic ointment is considered safer

and is prescribed for many chronic skin diseases. It is well suited for allergic dermatitis and urticaria. This drug is less likely to cause adverse reactions. However, it is not always effective. When there is a bacterial or fungal complication, the combined ointment Akriderm GK is used.

It is recommended to use the HA product

for acute symptoms of a dermatological disease with a short course. When the classic ointment turns out to be ineffective, its supplemented version is also shown. For bacterial and fungal infections - only Akriderm GK, since the classic remedy is useless in these cases.

You should not give preference to Akriderm GC just because it is “stronger”. Firstly, this does not make sense when the indications allow the use of ordinary ointment. Secondly, the cost of the HA product is almost 4 times higher.

Both medications can be purchased without a prescription, but self-medication is highly discouraged. Hormonal ointments have many side effects and contraindications. Before use, be sure to consult a doctor.

Reviews

Vladimir, Volgodonsk: I have been suffering from allergic dermatitis to household chemicals for more than ten years. A dermatologist recently advised me to try the Russian drug Akriderm. To my surprise, the pharmacy asked me to clarify which product was needed. I had to call the dermatologist. The doctor explained to me the difference between Akriderm cream and ointment. The cream is used for minor inflammation, and the ointment for severe exacerbation.

Alena, Voronezh: Perhaps only Akriderm quickly relieves pain and inflammation in psoriasis. Within a few hours, severe swelling and redness on the skin disappear. I am pleased with the low price. I’m already used to paying large sums for hormonal medications.