Cosmetics of the future: what are peptides
Since the beginning of the last century, “protein” cosmetics have been under the close attention of both developers and consumers, who prefer to know what exactly is in the next bright jar, and why this particular substance should help them keep their skin in good shape. You yourself probably know what collagen, keratin, elastin are and how often they are included in serums and creams. All these are squirrels, but of the “old generation”.
Another thing is peptides! Unlike other protein compounds, they have:
- simple structure - 2 or more chains of amino acids held together by a peptide bond (other proteins may contain 50 or more amino acids);
- miniature dimensions about 1 nm;
- relative stability, that is, the ability not to change its properties under the influence of external factors.
Due to their small size, peptides act more efficiently than other proteins
It is thanks to all of the above that peptides outperform heavy and large proteins in no time, penetrating into the deeper layers of the skin and reaching cells that are inaccessible to conventional cosmetic products. And then they begin their main task: they stimulate cells to divide, renew themselves and resist the aging process. In addition, peptides improve intracellular metabolic processes, have a beneficial effect on skin microcirculation, and promote the absorption of oxygen and other substances necessary for the skin. With regular use of cosmetics containing peptides, cells are rejuvenated, the walls of blood vessels are strengthened, skin metabolism is normalized, and the skin itself becomes fresher, tighter, more elastic, getting rid of wrinkles and inflammation along the way.
Note: peptides penetrate into the deeper layers of the skin more easily if its surface has been pre-treated with a scrub.
What do they do and what are the benefits of peptides for your facial skin?
As we age, collagen production decreases. As a result, your skin sags and loses its elasticity, and you get wrinkles. Incorporating peptides into your skin care regimen can help greatly.
Here's how peptides help your aging skin:
Peptides reduce skin aging
In a double-blind clinical study, researchers studied 20 women aged 40 to 62 years. They were given a formula containing 3% collagen-like peptide and 1% booster molecule. They applied the gel to their eye area for four weeks. The results showed a significant reduction in the surface area as well as the depth of wrinkles.
Peptides help reduce erythema
Erythema, or redness of the skin, can occur due to a variety of reasons, including infection, inflammation, or increased blood flow in your superficial capillaries. A six-month study of 20 subjects found that both carnosine (a dipeptide molecule) and N-acetylcarnosine (linked to the dipeptide carnosine) can help reduce erythema when applied to the skin. Researchers also found that these two peptides have antioxidant properties.
Improves skin firmness and elasticity
In 2 separate studies, the peptide was found to improve skin firmness and firmness and reduce skin sagging.
Peptides have anti-inflammatory effects
According to research, palmitoyl tetrapeptide-7 has anti-inflammatory effects on your skin. It suggests that this peptide reduces the secretion of IL-6, thereby reducing inflammation after UVB exposure. The mixture of palmitoyl tetrapeptide-7 and palmitoyl oligopeptide also improves the structure of the extracellular matrix (the network of extracellular macromolecules including glycoproteins, enzymes and collagen that supports cells). Read about the benefits of hyaluronic acid for the face.
There are about a hundred peptides. However, only a few are used for skin care.
Where to look for peptides
Today, peptide complexes are added everywhere: to products for the care of the face, neck, and décolleté; in eye serums; in micellar water for washing; in gels for hands and feet; in an ointment against spider veins and varicose veins. The presence of miniature proteins in the composition of a particular product will be indicated by the following inscriptions:
- palmitoyl-pentapeptide;
- palmitoyl-tripeptide;
- palmitoyl oligopeptide;
- palmitoyl tetrapeptide;
- acetyl hexapeptide-3.
Look for them at the very end of the list; peptides are added to cosmetics in small quantities due to their active action.
Many brands have begun to produce entire lines of products with peptides
The best peptides for facial skin
Everyday Peptides are mainly classified as:
Peptide Carriers
These are Myocept X-50, copper peptides, etc.
Carrier peptides love to carry manganese and copper to your skin. These trace elements help and boost collagen development, improve your skin elasticity, and help heal it. Copper peptides are commonly used in skin care creams.
Neurotransmitter Inhibitor Peptides
These are XEP-30, Palmitoyl Tripeptide-38, Palmitoyl tetrapeptide-28 Argireline, Syn-Ake, etc.
Neurotransmitter inhibitor peptides inhibit muscle contraction, giving your skin a Botox-like effect. If your muscles don't contract, there is no opportunity for wrinkles to form. However, this peptide only works on wrinkles formed by expression lines and not those caused by pollution, sun exposure, and other factors.
Enzyme Inhibitor Peptides
These are Trilagen, Trifluoroacetyl tripeptide-2, silk fibroin peptides, soy peptides, etc.
These peptides inhibit all the enzymes that break down collagen in your skin. This way your skin ages slowly. Most of these peptides typically inhibit the functions of matrix metalloproteinases or MMPs. This is a group of enzymes that break down collagen as it develops rapidly.
Signal peptides
These are Palmitoyl oligopeptide-7, copper peptides, Palmitoyl pentapeptide-4, Matrixyl-3000, etc.
These peptides typically send signals to the skin to boost the production of elastin, collagen, and any other proteins that keep the skin fresh and youthful.
Now the question is how do you get these peptides? Here is a list of foods you can include in your diet to increase the amount of peptides in your system.
Advantages and disadvantages of peptide cosmetics
The advantages of using cosmetics with peptides are obvious: they make it possible to restore a radiant appearance to the skin without resorting to such extreme measures as a syringe and scalpel. Baby peptides act gently, are rarely rejected by the body (practically do not cause allergies), stimulate the skin to produce natural collagen, trigger its regeneration processes and accelerate the healing of small wounds.
Minuses:
- products with peptides have a short shelf life - no more than 2-4 months - and require storage in the refrigerator;
- without the use of scrubs and peels, a cream with peptides may simply not penetrate through the upper stratum corneum of the skin to the deep-lying cells;
- the funds do not have a cumulative effect, so their use will have to be on a permanent basis.
At the same time, many cosmetologists are convinced that if you feed the skin with peptides without stopping, it will relax and stop reproducing its own collagen without encouraging “kicks”. So taking breaks from time to time, putting aside the cream with peptides for 1-2 months, is only useful.
Side effects of peptides for the face
When you start using peptide products, you may notice some side effects and symptoms.
These include:
- Redness
- Inflammation
- Itching
- Rash
To avoid this, always make sure to do a patch test before using the product. Also, before using any peptide, find out whether you are allergic to it or not. It is best to consult a dermatologist before using any skin care product.
Peptides may be the best anti-aging treatment you have ever encountered in your life. However, don't just buy any product that claims to contain peptides, especially when you're already using anti-aging skin care products. Talk to your doctor and take the time to prepare your skin for peptides.
Who needs cosmetics with peptides
The most suitable age for the first use of cosmetics with peptides is considered to be 35 years old, although a dry, problematic, aging face can be introduced to such products as early as 25–30 - it all depends on how early your face begins to send SOS signals. But after 50, the effectiveness of “peptide cosmetics” begins to decline.
Owners of oily skin should take note: for the production of creams with peptides, a base with increased fat content is usually used, which can lead to unpleasant consequences for you.
Video: cream with Botox effect
Natural sources of peptides in products
Milk
Milk is one of the most common sources of dietary peptides. Bioactive peptides found in milk were the first food peptides to be widely studied. Milk is rich in whey protein and casein. Once digested, both of these components can be processed into a range of peptides that have antimicrobial and therapeutic properties. Just be careful, as consuming dairy products can cause inflammation. Choose as many organic and grass-fed varieties as possible.
Eggs
These are rich sources of dietary peptides. IRW and IQW peptides have anti-inflammatory properties and also contain antioxidants.
Soybeans
Soy and many other beans contain peptides that are associated with numerous health benefits. Research claims that soy peptides have antioxidant and anti-fatigue properties. He also claims that soy peptide can increase type I collagen in your body.
Fish and meat
Fish, especially saltwater fish, are a rich source of essential peptides and proteins. Peptides in fish can prevent skin photoaging. Fish bones and skin are especially rich in collagen. Marine collagen is mainly used in skin care products and is a very effective free radical scavenger.
Even meats such as pork, beef and chicken are rich sources of bioactive peptides.
Nutrition is key to getting healthy, glowing skin. Taking peptides orally through foods and supplements improves collagen synthesis and skin hydration levels, and restores your skin's natural barrier.
The battlefield is the extracellular matrix.
Let's get acquainted with the extracellular matrix, this is important for understanding the principle of action of peptide cosmetics. The definition of matrix is given in an extremely simplified manner and in the context of this article. In fact, the matrix occupies about 25% of the volume of our body, its structure and functionality are much, much, more complicated than described here.
The extracellular matrix is the skin framework consisting of elastin, collagen, and hyaluronic acid. The quality of this frame determines the quality of the skin - the absence of wrinkles on the face, firmness, elasticity. Creative and destructive processes are constantly going on in the matrix, that’s how it’s structured. The builders are fibroblasts, the destroyers are special enzymes - metalloproteinases. Fibroblasts produce collagen, enzymes destroy it, fibroblasts produce it, enzymes destroy it, etc.
Fibroblasts are connective tissue cells that synthesize collagen and elastin; the amount of collagen and elastin, and therefore the quality of the matrix, depends on their activity.
Metalloproteinases are enzymes that destroy old, broken matrix components, clearing the way for cells. Collagen fibers fall under their destructive effect.
Aging and the appearance of wrinkles are a deterioration of the matrix structure, so most of the effects of anti-aging cosmetics are aimed at improving this structure. But wrinkles are different, just like the types and types of aging. To learn how to choose the right anti-aging product, read the article - Remedies for facial wrinkles.
Having described an extremely simplified model of the matrix, life and death of collagen, we will continue to talk about peptide compounds.
Geroprotectors for rejuvenation - how they can be dangerous
To avoid changing a given peptide chain (with a specific sequence of amino acids) by its rearranged variation, scientists have developed several carriers - substances that perform the function of attaching peptides to themselves unchanged and then detaching them in the body.
One of the carriers in cosmetology is hyaluronic acid. It allows not only to deliver peptides to the skin, but also to ensure their gradual release over a certain period of time. Such peptide therapy for cosmetic purposes actually ensures a full course, similar to sanatorium treatment: the peptides are released from the carrier gradually, since hyaluronic acid takes a long time to break down.
Geroprotectors for rejuvenation in the form of peptides allow:
- They activate exactly the cells for which they are designed.
- Active cells begin to produce the substances they need on their own.
- Cells “heal” themselves.
These processes are clearly visible when using peptides in cosmetology. Skin cells treated with peptides produce their own collagen, which restores elasticity to the skin and creates a lifting effect.
Neuropeptides used today in cosmetics additionally have a relaxing effect on individual tense areas, which improves skin regeneration.
Peptide complexes provide:
- Antioxidant protection.
- Moisturizes the skin.
- Protect the epidermis from harmful environmental factors.
Understanding the processes that we describe and can even evaluate with our own eyes, having tried it on ourselves - for the skin, it is easy to imagine how peptides work when they get into the cells of organs and tissues.
Geroprotectors for rejuvenation are used today in almost all industries related to human health. This is precisely the proof of their effectiveness and high safety. It is only a matter of time before the general public adopts peptides. Substances discovered in the 70s of the last century have not only not lost their relevance over the past 50 years, but have also significantly improved, expanding the list and methods of delivery to the necessary places in the body.
Results of using the peptide to improve immunity:
Another peptide complex, the use of which we often hear positive reviews and results from our clients. First of all, for frequent colds in children, secondly, as an increase in immunity in allergy sufferers, and of course it is worth remembering that this is a powerful cancer prevention.
Recall of the use of peptide for immunity against colds
I have never used drugs to support immunity before. A friend recommended the peptide to me. She felt much more energetic after using it, she even began to walk better (she had problems with her joints). In addition, now the beginning of winter is the most flu-like time, and the body needs to be kept in good shape. I’ve been using PEPTIDE for a month now – I don’t sneeze or cough.” Nina Minina, St. Petersburg
Andrey 02/05/2018
I am a partner of Rejuvital, and my whole family started using the company’s products. But this review is not about us. A friend of mine has twin children, 3 years old. They get sick endlessly! This winter I have already suffered from bronchitis twice, both in turn. Mom lost 10 kilograms. I gave them Peptoline 5, 2 drops per day. Before the New Year, the whole family came down with a sore throat: dad, mom, older sister. But the twins, with their immunity seemingly impaired by antibiotics, are not! Overall, the family is delighted! I think now Rejuvital is a regular customer
Negative reviews about Khavinson peptides, forum, discussion
Love
Good afternoon The packaging of the eye serum is simply disgusting! Every day I mine it like ore((The product is good, but such defects spoil everything. Is it possible to contact the manufacturers there with a proposal for improvement?
23.05.2017
We have taken your wishes into account and now the eye serum is being produced in a new convenient European-style packaging. Thank you for your offer.
DC Voronezh. A woman with rheumatoid arthritis contacted us (you recommended Endoluten, Kartalax, Revifort, Regenart). And at the St. Petersburg public reception, Vyacheslav Vyacheslavovich advised her and said that this disease cannot be cured with peptides.
It all started five years ago with an allergy (cough, itching), she was examined in Germany, it was discovered that the main allergen was birch pollen, they began to give her raftilin from birch pollen - her thumbs (joints) began to hurt. Then pain began in all joints. 4 years ago 3 months I was in the clinic, they started injecting Methotrexate (a drug used for cancer) weekly, suppressing the immune system, and they are still injecting it. After it there were severe exacerbations, he did not walk for three days after the injections. Nimesil (painkiller) eats in boxes. Some kind of rheumatoid coefficient - up to 160 (normal - 130).
Let's try to help! I really hope for a detailed answer from Egor Mikhailovich
Answer: Rheumatoid arthritis is a severe autoimmune disease that has a GENETIC cause. Since peptide bioregulators work with the genome, a complete cure cannot be expected. No methods will cure completely; we can only talk about improving the quality of life and reducing the severity of the pathology. Peptide bioregulators are exactly what can achieve maximum effect in this situation. The cause of the pathology is that the immune system attacks its own cartilage tissue, destroying it, which causes inflammatory processes. Therefore, we must support the connective tissue (so that it “better resists”) and “hold back” the immune system - that is why the patient was prescribed a drug that suppresses the immune system.
I can recommend peptide bioregulators:
Endoluten (normalization of the entire endocrine system, including immunity)
Glandocort (it is the adrenal glands that produce prednisolone, a hormone that suppresses the activity of the immune system)
Thyrogen - improper functioning of the thyroid gland is often the cause of autoimmune processes. Kartalax or Sigumir - maintenance of connective tissue.
Regenart or Chondromix - nutrition of cartilage tissue.
Revifort (not as an oncoprotector but as an anti-autoimmune drug).
I would start with Glandocort, then after the condition has normalized, I will need to “work out” the pancreas: Suprefort (since all painkillers kill the gland), someday choose the time and find funds for the liver: Svetinorm or Ovagen. It is the liver that is responsible for the restoration of cartilage tissue.
PC No. 3 (restoration of normal functioning of the immune system) will not interfere.
I was glad to help, Egor.
Woman, 46 years old:
Good afternoon A severe pancreatic spasm occurred. She began to treat herself and the condition greatly worsened. Stopped sleeping. The psychotherapist prescribed Alprazolam and Eglonil. Eglonil caused a terrible aggravation, but on Alprazolam I was at least able to sleep. But it was not addictive because I drank a lot of natural drugs and took Alprazolam for almost 2 months, but it also depressed the liver. Neurologists advised him to abruptly stop taking Alprazolam, and the pharmacist said that he should take something weaker, such as Atarax. I tried Teraligen on the advice of another neurologist - it caused severe aggravation of the liver and pancreas.
Then I learned from an acupuncturist about NCRPRIZ, started drinking and on the 2nd day I felt relief from Svetinorm and, initially, from Endoluten. I picked up many others: Stamacort, Ventfort, Cerluten, Suprefort, Thyreogen, Imusil, Christagen and Ardiliv. There were improvements for a week. Then I went to a homeopath - she, using a precise instrument, determined that for now I only need to drink Ardiliv and Svetinorm, and cleanse myself from the tranquilizer. Endoluten did not give the desired results - I took it for a week and did not sleep for a week. At first there were urges to sleep, but I knocked them down with something: either with a homeopathic remedy, or I caught a cold and was treated and did not sleep during the illness.
Please advise what to do!
Answer: 1) All the pharmaceuticals you listed are drugs that suppress the functioning of the nervous system, each of them has a bunch of side effects. Drugs that reduce the sensitivity of nerve receptors hasten the development of impaired glucose tolerance. This happens because the BRAIN, WITH THE HELP OF RECEPTORS, determines when and how much to produce: insulin, glucagon, adrenal hormones, melatonin and digestive enzymes. By using all of the above drugs, you make it so that your body simply does not have information about the CONDITION OF YOUR BODY.
2) Regarding the homeopath: I don’t know how a person who is not a specialist in peptide bioregulators can say which drugs are worth taking and which ones are not. Moreover, we know nothing about any devices that can measure the effectiveness of drugs.
3) Regarding Endoluten: most likely you violated the recommendations for taking it. For example, if you are not going to go to bed on time, there is no point in taking Endoluten.
4) You urgently need to restore the functioning of the nervous system: Pinealon + Mesotel, then Cerluten. Take Glandocort (adrenal glands), and then return to Endoluten - you drink it once (in the morning) every 3 days. Peptide bioregulators are not hormones; they do not work quickly, but they are very powerful and WITHOUT SIDE EFFECTS.
5) Everything you bought is good, just don’t start taking it all at once - it may not be very “pleasant”. Take your time - add the next drug after 3-4 days. This will make it easier for you to enter the revitalization process. Be patient and do not rush to blindly follow the advice of various “experts”.
Svetlana
Hello! I placed my first order of peptides for an elderly man who had been suffering from ankylosing spondylitis for 28 years. I would like to ask why peptides for the veins and brain are included in the 3-stage course of treatment, but there is nothing for the treatment of joints? Is this a disease of the musculoskeletal system? Please explain what's what.
Answer: Ankylosing spondylitis (ankylosing spondylitis) is a chronic progressive disease manifested by inflammation of the joints of the spine. Prolonged inflammation leads to impaired movement in the joints.
In addition to limiting the mobility of the spine, if left untreated, the disease spreads to other organs and systems.
Therefore, it is extremely important to approach therapy comprehensively: use dietary supplements and drug therapy in combination.
A complex of peptide bioregulators of the vascular wall, central nervous system and peripheral nervous system accelerates the restoration of joints and neuromuscular conduction, and also reduces the degree of damage to the nervous and cardiovascular systems during the development of the disease.
Recall of the use of a peptide to improve immunity for allergies
I am a group II disabled person; in the 1990s I underwent three operations on my lungs; in the end, the right one had to be removed. The treatment process was complicated by acquired allergies to many medications and foods. Given the reduced immunity, postoperative complications and allergies, life was simply scary. Immune peptide and meso cocktail, my husband and I have been taking them for more than two years. Gradually, my condition stabilized, I began to get sick less, and my immunity increased. And, most importantly, the fear that I would never get out of my illnesses went away. Today, all my friends who remember me mostly in a depressed state note that I have become incomparably more cheerful and fifteen years younger! Natalya Vilchek, 56 years old
