Review of the drug Diprospan
Diprospan
Diprospan is a hormonal medicine for intramuscular administration. Gives results in the treatment of psoriatic arthritis and severe forms of psoriasis.
Active ingredient (composition)
Betamethasone is a potent hormonal agent (glucocorticoid).
Release forms
Suspension, solution for injection.
Indications for use
- psoriasis;
- psoriatic arthritis.
Operating principle
The drug has a complex effect:
- Anti-inflammatory.
- Immunosuppressive.
- Antiallergic.
Contraindications and restrictions
- increased sensitivity;
- with caution and under strict medical supervision: during pregnancy and lactation;
- infectious arthritis, unstable joint;
- systemic mycoses;
- cannot be injected into infected surfaces and into the space between the vertebrae, intravenously or subcutaneously;
- hypothyroidism, liver cirrhosis;
- peptic ulcer of the stomach and duodenum, renal failure;
- eye diseases;
- recent intestinal anastomoses;
- nonspecific ulcerative colitis;
- arterial hypertension;
- diverticulitis;
- abscess or other purulent infections;
- myasthenia gravis;
- osteoporosis;
- thrombocytopenic purpura (recommended for intramuscular administration).
Betamethasone (the active ingredient of Diprospan) is used only for a short course, since this substance causes the most pronounced side effects.
Duration of treatment
The treatment regimen and dose are individual for each patient, 4 weeks or more (with a break between injections). Yandex
Side effects
- increased irritability, depression, euphoria, personality disorders, insomnia;
- hiccups, ulcers and erosions of the gastrointestinal tract, flatulence, pancreatitis;
- dizziness, headache;
- convulsions, increased intracranial pressure with swelling of the optic disc; increased intraocular pressure;
- glaucoma, posterior subcapsular cataract, exophthalmos; rarely - blindness;
- lipomatosis, weight gain;
- angioedema, anaphylactic reactions, shock, low blood pressure;
- heart failure, increased blood pressure;
- petechiae, ecchymosis, striae, dermatitis, increased sweating, steroid acne;
- osteoporosis, muscle weakness, vertebral compression fracture, steroid myopathy, tendon ruptures, joint instability and others;
- steroid diabetes mellitus or manifestation of latent diabetes mellitus, increased need for insulin or oral hypoglycemic drugs, Itsenko-Cushing syndrome, secondary adrenal insufficiency;
- disorders of intrauterine development, delayed growth and sexual development in children, menstrual irregularities;
- rarely: subcutaneous and cutaneous atrophy, aseptic abscesses, hypo- or hyperpigmentation, neurogenic arthropathy.
Diprospan for psoriasis: reviews
Review from user ravnovesie about the drug Diprospan
Review from user andre about the drug Diprospan
Review from user DJONI-07-61RUS about the drug Diprospan
Review from user Kotyuk about the drug Diprospan
Medical research on the drug
There is no information in open sources.
Price
Price in Moscow - 803-887 rubles. per pack 5 pcs. (ampoules).
What is it used for?
It is still often used in medical practice to treat diseases of the musculoskeletal system, including joints. This is a drug that can be used to quickly relieve inflammation or prevent the proliferation of connective tissue. It effectively suppresses immunological and allergic reactions and acts even when other drugs are powerless, but, being a glucocorticosteroid hormonal agent, it has serious side effects, so it should be used with extreme caution. In addition, its long-term use should be excluded - the number of side effects increases many times over.
Conclusion about the drug
Diprospan is a powerful long-acting hormone.
Reviews speak of rapid action, psoriasis disappears within 2-3 days, but remission can last only a week. Then the disease returns with a vengeance.
Injections for psoriasis (Diprospan) are prescribed only by a doctor: when other remedies do not work, in severe forms of psoriasis and psoriatic arthritis.
The effects on the body and side effects are stronger than those of methotrexate. First, traditional methods and treatment at home (in consultation with a doctor) are used to treat psoriasis.
The use of Diprospan for psoriasis is a last resort.
Psoriasis and diprospan
Svetlana, Uglich
5851 views
January 28, 2021
Hello dear doctors! My husband is 46 years old, and for many years he has been suffering from extensive psoriasis, with an exacerbation of 90 percent of the body. I tried everything prescribed by doctors, from ointments, physiotherapy, to GCS, and was treated for years to no avail. The only thing I haven’t tried is drugs from the group of monoclonal antibodies - they are insanely, prohibitively expensive. 3 years ago, during the next exacerbation, our dermatologist prescribed a treatment regimen with diprospan intramuscularly: 1 double injection, after 5 days another 1, but already 1 ampoule, then after another 5 days 1 ampoule, and so on 5 injections per month at intervals of 5 days , and the first injection is in double dosage. And oh, miracle, clean body, happy husband. This miracle was enough for about 3-4 months, and again a month of Diprospan injections, etc. At the moment, remission is less than a month, and I have collected all the side effects: +27 kg in 2 years, very large belly, stretch marks, weakness, Cushing is most likely present. Recently we had an FGD, an MRI of the adrenal glands and an MRI of the pituitary gland, everything is fine, I tested daily urine for cortisol - there is almost no cortisol, the adrenal glands do not produce it (doctors say that it will gradually return to normal, but what if every month there is a course of diprospan? Glucose is on the edge , but tolerable 6, 5. Now again he is completely covered with huge plaques, suffers from pain and from complexes, works with people, and is embarrassed even by me. I do my best to dissuade him from the next course of diprospan, there is less and less sense (the feeling that there is already a constant exacerbation he has), and there are more and more side effects, but you can’t convince him, he says, it’s better to take 2 weeks, but to feel like a person. Our dermatologist at an in-person appointment said to be treated with what helps, that is, the diprospan prescribed by her, because it is incurable. The regional endocrinologist says to urgently get off the hormones, but they don’t offer anything to replace them, and they don’t offer a plan for “getting off.” The regional dermatologist suggested Stelara and flying to the Dead Sea. Cosmically expensive! What should we do? I’m insanely afraid for my husband. Healthy lifestyle, does not smoke, does not drink, eats a healthy diet, periodically diets. What to do, what to do? Should Diprospan continue with the same scheme? I'm afraid that it will kill his joints, bones, etc. + This Cushing's syndrome still does not go away. Or something that might be less aggressive. Or is the injection schedule different? Or try to jump from it, again according to what scheme and on what? Concomitant hypertension (Valsakor) and asthma (Symbicort) for life. Please help me with advice, I beg you! Thank you in advance for your answers!
The question is closed
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Belgian glucocorticoid Diprospan
The drug Diprospan is a simple corticosteroid for systemic use.
It is used in various fields of medicine as part of monotherapy and complex hormone replacement therapy, and has a pronounced therapeutic effect. It is most widely used to treat joints. Inflammation, trauma, degenerative processes, age-related changes in cartilage and muscle tissue, accompanied by limited mobility, respond well to GCS therapy. The drug is used to treat moderate and severe forms of allergies.
Composition, pharmacodynamics and dosage forms
Betamethasone sodium phosphate is an active participant in hydrolysis. Once in the body, the compound is instantly absorbed from the injection site, triggers the therapeutic mechanism and is eliminated very quickly.
Betamethasone dipropionate has an indirect effect, due to which a long-lasting and lasting therapeutic effect is achieved.
The kidneys are involved in the elimination of betamethasone compounds.
Ukrainian pharmacies sell Diprospan ampoules. The package contains 5 sealed glass containers with injection suspension, 1 ml each. It is possible to sell ampoules individually. Dispensed by prescription.
Note!
The description of the drug Diprospan on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.
When is Diprospan prescribed?
Glucocorticosteroid therapy can be primary or additional for a wide range of conditions:
dermatology of any etiology (psoriasis, eczema, atopic dermatitis, etc.);
- diseases of the musculoskeletal system, connective tissue (arthritis, arthrosis, bursitis, epicondylitis, torticollis, fasciitis, etc.);
- allergies (seasonal rhinitis, bronchial asthma, allergic bronchitis, hay fever, reactions to insect bites, urticaria, etc.);
- hemoblastoses in adults and children;
- in combination with mineralocorticosteroid therapy for adrenal insufficiency;
- pathological changes in blood composition;
- nephritis and nephrotic syndrome;
- states of shock.
