Comparison of Botox and biorevitalization: which procedure should be performed first and which after?

Grishko O.N.

Dermatocosmetologist, specialist in laser and injection techniques

When solving various aesthetic problems in cosmetology, one way or another, a combination of hardware methods with injection methods is used: biorevitalization, botulinum therapy, plasma lifting.

It is important to follow the correct sequence of manipulations, determined by the possibility of achieving the desired results, the principle of action and the duration of the effect of the methods and drugs used. And of course, always remember the main principle of a cosmetologist: “do no harm.”

If the sequence and technique are followed, the combination of fractional thermolysis with injection methods can enhance the effect or speed up the results.

Characteristics of procedures

Although both of these procedures have the same goal - facial rejuvenation, their principles of action are fundamentally different.

Botox therapy

Botulinum toxin is the main component of the injection. The action is to block nerve impulses to the muscle, causing the muscle to relax and wrinkles to smooth out.

Most often, botulinum toxin is used as an injection into the facial muscles to eliminate wrinkles on the forehead, around the eyes, and on the bridge of the nose. Expression wrinkles around the mouth are rarely injected, since the muscles in this area are located close to each other and the risk of error is very high (read about Lip Botox, results and side effects of the procedure here).


Deep wrinkles that do not have a facial character cannot be completely smoothed out with Botox. However, such injections are a good prevention of the appearance of new facial wrinkles. The result after the procedure will be finalized in two to three weeks. We talked about how long the effect of Botox on the face lasts and when it is necessary to prolong the effect in a separate article.

Botulinum toxin does not linger in body tissues. The drug, having an effect on the muscles, is eliminated from the body within 1-2 hours.

Women believe that Botox injections are only suitable for women over 45 years old . However, cosmetologists claim that botulinum toxin injections are available for use from the age of 18, if necessary.

We invite you to watch a video about what botulinum toxin injections are:

Are you interested in this procedure? Read our other articles about Botox for eyebrows, for lips, as well as about botulinum toxin injections into the nasolabial folds, neck and armpits.

Biorevitalization injections

Biorevitalization is a procedure aimed at giving the skin its former elasticity and firmness, improving complexion, and slowing down aging. Biorevitalization is a subcutaneous injection of hyaluronic acid. Hyaluronic acid is a hydrophilic substance that attracts liquid and retains it. This way, the skin cells are filled with moisture not from the outside, but from the inside.

There are two types of biorevitalization - laser and injection:

  • During the injection procedure, the required amount of hyaluronic acid is injected into problem areas on the patient’s face.
    The first effect in the form of smoothing wrinkles and moisturizing the skin is noticeable immediately.
  • During the laser procedure, a composition containing hyaluronic acid is applied to the client's skin. The components of the drug change the structure under the influence of the laser and penetrate into the deep layers of the skin through the pores. The effect occurs gradually over 1-2 weeks.

Cosmetologists do not recommend performing biorevitalization procedures for women under 30 years of age.

We invite you to watch a video about what biorevitalization is:

What is the difference

With age, the skin loses its elasticity and healthy appearance, and external products help only partially, without solving the problem. Then women turn to a cosmetologist, and they are faced with a choice - Dysport or biorevitalization.

Dysport is the injection of botulinum toxin A into the muscles, which paralyzes them. They stop shrinking, and even deep wrinkles disappear on the face. Because of this, facial expressions are disrupted - it is no longer possible to smile or frown at full strength. The procedure is similar to Botox, but different drugs are used. Dysport is produced in France and is slightly cheaper.

Biorevitalization is a subcutaneous injection of hyaluronic acid. The name consists of 3 components: “bio” - natural, “re” - renewal, “vita” - life.

Hyaluronic acid is a substance familiar to our body. It is responsible for retaining water molecules and moisturizing the skin, for its elastic, youthful appearance. After 25 years, the production of hyaluronic acid slows down, so it is necessary to replenish its reserves artificially.

Comparison of action and other parameters

Anti-aging procedures have the same goal, but act differently.

BotoxBiorevitalization
PriceIn Moscow, the cost of injections in the forehead, between the eyebrows and in the area around the eyes is 30 thousand rubles, in St. Petersburg - from 26 thousand rubles.Depending on the cost of the drug, the price for biorevitalization in Moscow starts at 11 thousand rubles. In St. Petersburg, the procedure costs from 6 thousand rubles.
EfficiencyBotox injections effectively relieve a woman of facial wrinkles on the upper part of her face. The skin looks elastic and youthful. The first effect in the form of filling small wrinkles and filling the skin with moisture comes immediately after the procedure. After 2 weeks, the skin begins to produce its own hyaluronic acid, takes on a fresh and youthful appearance, and deeper wrinkles are smoothed out.
Duration of saving the resultTo maintain the rejuvenation effect, the procedure must be repeated every 4-5 months.A course of 3-5 biorevitalization sessions to maintain the filling effect must be carried out once every 6 months.

Prices:

Fractional thermolysis

Fractional thermolysis of the face:
— Ablative laser (Erbium)15,000 rub.
— Non-ablative laser (Neodymium)12,000 rub.
Fractional thermolysis of the forehead5,000 rub.
Fractional thermolysis of the eyelids of both eyes6,000 rub.
Fractional thermolysis of the cheeks10,000 rub.
Fractional thermolysis of the neck - promotion!!!8,000 rub.
Fractional thermolysis of the décolleté15,000 rub.
Fractional thermolysis of the face and neck - promotion!!!18,000 rub.
Fractional thermolysis of the face, neck and décolleté - promotion!!!25,000 rub.
Fractional thermolysis of the mammary glands12,000 rub.
Fractional thermolysis of abdominal skin15,000 rub.
Fractional thermolysis of the shoulder - inner part (both arms)15,000 rub.
Fractional thermolysis of hand skin10,000 rub.
Fractional thermolysis of the buttocks (two sides)15,000 rub.
Fractional thermolysis of the thigh - inner part (both legs)20,000 rub.
Fractional thermolysis of the thigh - outer part (both legs)15,000 rub.
Fractional thermolysis of the knee areas (both legs)12,000 rub.
Fractional thermolysis of the intimate area New!!!5,000 rub.
Fractional thermolysis of scars (1 sq cm)1,000 rub.
Fractional thermolysis of scars from 2 cm or more (1 sq cm)500 rub.
Laser (carbon) peeling6,000 rub.

Discounts when paying for the course (3 procedures):

Fractional thermolysis of the face:
— Ablative laser (Erbium)40,000 rub.
— Non-ablative laser (Neodymium)30,000 rub.
Fractional thermolysis of face and neck45,000 rub.
Fractional thermolysis of the face, neck and décolleté60,000 rub.

What is better to choose, in what case?

Botox and biorevitalization cannot be put on the same scale - these are completely different procedures.

  • Botox only blocks facial expressions and removes the cause of the formation of facial wrinkles in the upper part of the face.
    If a large number of wrinkles appear on the forehead and around the eyes in response to emotions, this is a reason to resort to the help of botulinum toxin.
  • Hyaluronic acid, in turn, fills wrinkles on any part of the face: at the mouth, on the forehead, on the cheeks, around the eyes. Expression wrinkles cannot be eliminated using biorevitalization. Biorevitalization is carried out when it is necessary to slow down the aging of the skin and hide the first signs of aging, make it moisturized and elastic, and fill out wrinkles.

Indications for use

When trying to choose what suits you best: Botox or mesotherapy, it is impossible not to discuss the scope of application of both methods. The mesotherapy procedure is characterized by maximum versatility. It is used for:

  • wrinkles, sagging and other skin defects caused by the aging process;
  • oily skin with enlarged pores;
  • various diseases such as acne, rosacea;
  • overweight and cellulite.

Among other things, this technique can be used as an auxiliary technique for the treatment and restoration of skin after aggressive external intervention (for example, cosmetic peelings).

Indications for the use of mesotherapy - wrinkles, sagging and other skin defects caused by the aging process

The range of problems that Botox is designed to solve is not so diverse. It is primarily used to eliminate wrinkles, but can also be used to reduce sweating in certain areas of the body.

What to do first?


For effective anti-aging therapy, experts advise using a set of procedures, but they must be performed in strict accordance with the plan. Cosmetologists advise to carry out the biorevitalization procedure first , then use botulinum toxin injections.
It is advisable that both procedures are carried out by the same specialist, who clearly knows the names and properties of the drugs injected into the skin. This way you can avoid unpredictable side effects.

Efficiency comparison

Each procedure has its own special effect on the skin and has a whole list of advantages and disadvantages. The difference in effectiveness of each method is detailed in the tables.

Botulinum therapyBiorevitalization
FaceliftEvening out complexion
Elimination of nasolabial foldsReturn of tissue tone
Smoothing out deep wrinklesSmoothing out fine wrinkles
Elimination of strabismusElimination of sagging skin areas
Muscle relaxationRestoration of water and electrolyte balance in tissues
Elimination of eyebrow asymmetryUniform distribution of subcutaneous fat
Eye shape correction, drooping eyelid liftFace oval tightening

Is it possible to perform both procedures on the same day?

The drugs affect different tissues, but this does not mean that they can be used simultaneously. Experts do not recommend combining these procedures and performing them on the same day .

What will be the consequences if carried out simultaneously?

Any injections cause a reaction in the body in the form of swelling, and carrying out two procedures at the same time increases the risk of severe and prolonged swelling of the face.

Botulinum toxin immobilizes the muscle and slows down metabolic processes, while the action of hyaluronic acid is aimed at uniform distribution under the skin and “attracting” a large amount of moisture. So Botox literally negates the effect of biorevitalization.

Recommendations before the Botox procedure

At the very beginning, the doctor will invite you for a detailed consultation. He needs to obtain detailed information about the person’s face and body

It is very important to rule out any side effects and also get answers to the following questions:

  • how many times have you had Botox before;
  • presence of pregnancy or lactation;
  • presence of serious diseases;
  • the presence of allergic reactions to medications;
  • current drug therapy.

The doctor will ask in detail what effect the patient expects from the procedure. The latter needs to indicate which areas are of most concern. In some situations, it is additionally recommended to undergo other anti-aging procedures. You need to be frank with the doctor; you cannot keep silent about any secret.

You should stop taking blood thinning medications several weeks before the procedure. Try to limit vitamin E, ibuprofen, aspirin, and fish oil. This will help reduce the risk of possible complications. Ban yourself from alcohol for a few days.

How long after some injections are others allowed?


Botulinum therapy is carried out 3-4 weeks after the end of the course of hyaluronic acid injections .
By this time, the filler will be evenly distributed under the skin and will have maximum effect. The interval between procedures is determined by a specialist. It depends on the composition of the drugs and the individual characteristics of the patient.

Is it possible to do biorevitalization after Botox?

The doctor selects the sequence of rejuvenating techniques based on the characteristics of the client’s skin condition. Therefore, a specialist often first recommends using botulinum toxin and only then - preparations based on hyaluronic acid.

The interval between procedures performed in reverse order remains the same. There is only one exception, and it is typical for all cases. If you do not know the name of the drug that was administered to you at the beginning, you should absolutely not experiment. This can lead to unpredictable consequences. To avoid this, when going for a consultation, take the documents issued by the doctor for the medications he has previously used. At the end of the procedure, each specialist must hand them over to you. This is part of the gold standard of customer service.

Biorevitalization and mesotherapy in questions and answers

Biorevitalization and mesotherapy in Gomel is available in our medical clinic. You can see the price for these services here, and in this article we decided to tell you in more detail about what these procedures are and who will benefit from them.

After sun exposure, the problem of dehydration and dry skin comes to the fore. UV rays have a negative effect on skin cells - fibroblasts, which are responsible for the production of hyaluronic acid and collagen. Hyaluronic acid is a natural skin moisturizer, and after active tanning its amount noticeably decreases. In the summer, a large number of patients go to the medical center to see a cosmetologist in order to moisturize the skin and restore its radiance. To improve skin turgor and color, biorevitalization and mesotherapy are recommended. Before the procedure, an examination and consultation are required, during which the cosmetologist recommends the necessary drug and answers the patient’s questions. Below are the most pressing questions. What is the difference between biorevitalization and mesotherapy?

Facial mesotherapy and biorevitalization are methods for correcting aesthetic skin imperfections using the injection of hyaluronic acid.
The difference lies in the use of hyaluronic acid preparations of varying concentrations and molecular weights. For biorevitalization, preparations with a concentration of hyaluronic acid are used, usually from 1 to 3%. Papules after the procedure stay on the skin longer, the interval between procedures is usually 2 weeks, and the number of procedures is less. In mesotherapy preparations, the concentration of hyaluronic acid does not exceed 1%, therefore, to achieve an aesthetic result, a larger number of procedures are necessary with an interval of 1 week. The course of mesotherapy procedures is designed for 6-8 sessions, and the course of biorevitalization is on average 3-4 procedures. At what age can biorevitalization and mesotherapy procedures be performed?
The procedure is performed only if there are indications for it.
Considering the fact that the production of one’s own hyaluronic acid begins to decline from the age of 28 and the first signs of skin aging appear, biorevitalization is usually carried out after 30 years. But sometimes, to restore skin turgor, biorevitalization and mesotherapy are performed in younger patients. A decrease in skin turgor occurs with excessive use of tanning, sudden weight loss, or after a long illness and prolonged stress. Is it necessary to carry out a course or is one procedure enough?
A course of procedures is necessary to change the morphofunctional characteristics of the skin and achieve maximum aesthetic results.
The course is usually 3-4 procedures with an interval of 2 weeks, maintenance - 1 procedure every 3-4 months. One-time procedures are carried out for preventive purposes before traveling to hot countries or after returning from active sun. What complications can occur after biorevitalization and mesotherapy ?
Biorevitalization and mesotherapy are a safe and predictable procedure.
A carefully collected medical history and observance of intervals between procedures can avoid complications. Of the side effects, the most common are microhematomas, which can be avoided by not performing the procedure in the first 3-4 days of the menstrual cycle, while taking aspirin, citramone and other blood thinning drugs. Also, you should not do the procedure if the patient drank alcohol the day before. How long does the effect last after biorevitalization and mesotherapy, and what does it depend on?
The duration of the effect most often depends on the patient’s age and lifestyle.
Concomitant pathologies, uncontrolled tanning, stress, sudden weight loss, frequent air travel and time zone changes reduce the duration of the effect of the course of procedures. Also, the duration of the effect is affected by compliance with the intervals between procedures. If the procedures were irregular and isolated, the effect will quickly fade away. Is it possible to remove nasolabial folds with the help of biorevitalization and mesotherapy?
Nasolabial folds can be removed only with the help of stabilized hyaluronic acid filler. This procedure is called contour plastic surgery.

How long after biorevitalization and mesotherapy can photorejuvenation be done?

Photorejuvenation can be carried out no earlier than 7-14 days after biorevitalization and mesotherapy.
The duration of the intervals between procedures depends on the composition of the drug and the aesthetic condition of the patient’s skin. Is it necessary to perform hyaluronic acid injections with anesthesia?
No, not at all necessary.
It all depends on individual sensitivity and pain threshold. Many patients tolerate the procedure well and do not require pain relief. But, if you are doing the procedure for the first time and are afraid of injections, then it is better to apply anesthesia to the treated areas. Typically, Emla cream is used for anesthesia, which is applied under the film for 20 minutes. Is the procedure carried out in the summer?
Yes, it is carried out.
In summer, UV rays damage skin cells, it becomes dehydrated and loses turgor. In summer it is necessary to use sunscreen. It is not recommended to carry out the procedure earlier than 10 days after returning from active sun, and also to sunbathe in a solarium after the procedure for 7-10 days. Are hyaluronic acid injections performed in the area around the eyes?
Yes, it is carried out. Currently, a cosmetologist’s arsenal includes a large number of drugs developed specifically for the area around the eyes. You can decide on the choice of drug after consultation and examination. Consultation at our medical center is free.

Biorevitalization, mesotherapy and other procedures

Continuing the topic of such current procedures as biorevitalization and mesotherapy, I would like to consider combining them with other cosmetic procedures. Most often, questions arise about the combination with botulinum toxin preparations (Botox, Dysport) and peelings. Let's look at these questions in more detail.

Biorevitalization, mesotherapy and botulinum therapy.

Expression wrinkles can begin to form at an early age, when there are no indications for visiting a beauty salon. They can occur in different skin types, are associated with tension in certain facial muscles and often make young girls think about their correction. At the same time, we can see wrinkles on skin that is not prone to hyperactive facial expressions, often this is a dry and dehydrated skin type, as well as the condition of the skin after active sun exposure - as a result of photoaging. And in this case, the choice of the method of biorevitalization or mesotherapy here will be absolutely justified. In order to adequately assess the condition of your skin and choose the most appropriate correction method, let's define the definitions of these procedures. So, Botulinum therapy is an effective therapy for facial wrinkles, which is based on relaxing the muscle by injecting botulinum toxin (Botox) into it. Biorevitalization and mesotherapy are physiological prevention and correction of skin photoaging. Is it possible to combine these methods? Yes, it's possible. If at the same time there are signs of increased dryness of the stratum corneum of the epidermis, dehydration of the dermis, accompanied by a decrease in elasticity and sagging tissue, combined with expression wrinkles. In the absence of facial wrinkles, it is not advisable to inject botulinum toxin. And, conversely, biorevitalization and mesotherapy in young patients in the absence of signs of skin dehydration, decreased tone and photoaging is also inappropriate. But - IMPORTANT - IT IS NOT ADVISABLE TO COMBINE THESE TWO PROCEDURES AT THE SAME TIME! Why? When botulinum toxin is injected into a muscle, it relaxes, as a result of which the drainage of tissues and skin is disrupted. Consequently, for some time the outflow of blood and lymph from this area will be impaired and there may be slight swelling of the tissues. And biorevitalization and mesotherapy involve the introduction of a hydrophilic, that is, water-attracting, gel material, and this will also increase tissue swelling. Swelling will be especially noticeable in the area around the eyes. Therefore, the main condition for the compatibility of these methods is compliance with the required intervals between procedures. It is preferable to carry out botulinum therapy at the end of the course with biorevitalization and mesotherapy - after 2-3 weeks. A shorter interval between procedures is only permissible if the “mesobotox” technique is chosen, in which the dose of botulinum toxin is much lower and there will be no pronounced relaxation of the facial muscle. After botulinum therapy, biorevitalization and mesotherapy can be done after 3-4 months, when muscle movements are already slightly restored and the risk of edema is much less. What to do if tissue swelling does develop? Limit evening fluid intake and conduct a short course of physiotherapeutic procedures. But at the same time, tissue drainage and the removal of hyaluronic acid are enhanced, which negates the effect of biorevitalization.

Biorevitalization, mesotherapy and peelings

It all depends on the depth of skin damage caused by peeling or some other damaging agent. If deep or medium peeling, laser resurfacing or dermabrasion is planned, then a course of biorevitalization and mesotherapy before these procedures is absolutely justified. Preliminary preparation of the skin before an aggressive procedure will increase the adaptive capabilities of the skin, which will not only facilitate its healing after peeling, but will also direct it in the right direction and ensure high-quality restoration of the skin. This is especially important under unfavorable environmental and climatic conditions, the presence of bad habits (smoking), and an unbalanced diet. If a course of superficial peeling is carried out in young and middle-aged patients with relatively normal skin condition, then there is no need to include biorevitalization and mesotherapy in the preparatory period. If a decision is made and there are indications for a course of preventive biorevitalization and mesotherapy before an aggressive procedure, then the course must be completed in 10-14 days if ordinary hyaluronic acid was used, or in 14-21 days if hyaluronic acid ester preparations were used. As a restorative therapy after peeling, biorevitalization and mesotherapy can be used immediately after complete regeneration of the epidermis, sometimes after 2-3 days, if the procedure did not damage the epidermal barrier, for example, after laser, photo and RF exposure. Peeling and biorevitalization are not carried out simultaneously in one procedure. The anti-aging effect of a combination of these two procedures is always brighter. It is especially pronounced with a combination of biorevitalization and peelings with glycolic acid. Also, an important result of such a procedure will be, first of all, an increase in the safety of peeling. Skin that is carefully prepared for damage tolerates injury easily and is restored efficiently, which gives a wonderful aesthetic result. The risk of developing post-peeling pigmentation is significantly reduced. In conclusion, I would like to note that biorevitalization and mesotherapy are not just another injection method of introducing drugs into the deep layers of the skin. At one time, he made a revolution in therapeutic cosmeology. The main goal of biorevitalization and mesotherapy is to restore normal metabolism in intercellular structures without disturbing the natural regenerative mechanisms. Biorevitalization and mesotherapy can be performed even on patients with sensitive skin prone to allergic reactions. Biorevitalization and mesotherapy have a minimal number of contraindications. Moreover, it often allows one to eliminate existing contraindications to certain aggressive procedures.

Useful video

Watch this video about what to choose: Botox or hyaluronic acid for facial skin.

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