From this article you will learn:
- Baziron AC gel for acne – composition analysis,
- instructions for use,
- reviews of Baziron AS from dermatologists.
Baziron AS is an antimicrobial drug in the form of a gel for external use, which is intended for the treatment of acne (papulopustular form of acne). The active component of the drug is a bactericidal component such as “benzene peroxide”, which effectively affects the bacteria involved in the formation of acne. These include primarily the bacteria Propionibacterium acnes (P.acnes) and Streptococcus epidermidis.
Reviews from dermatologists about the drug Baziron for acne indicate that this drug is the gold standard for acne treatment. To date, there are no strains of P. acnes or S. epidermidis bacteria that are resistant to benzoyl peroxide, but you should understand that acne cannot be treated with benzoyl peroxide alone. And we will always combine the drug Baziron with topical retinoids (Klenzit or Differin), and sometimes also with antibiotics.
Photos of Baziron AS gel packaging –
The Baziron AS® trademark belongs to a pharmaceutical company (Switzerland), but production is located in Italy. There are 3 versions of the release form - gel with a concentration of benzoyl peroxide of 2.5, 5.0 and 10%. The drug is available over-the-counter and can also be used in patients over 12 years of age.
How much does Baziron AS cost in pharmacies, analogues:
For Baziron AS, the price in pharmacies will average from 800 rubles (per tube of 40 g). It should be noted that all forms of release cost almost the same - regardless of the concentration of benzoyl peroxide. The price is for 2022. This drug has no cheap analogues in Russia, or indeed any direct analogues. Cheaper, you can only buy cleansers with benzoyl peroxide, but this is not very effective and is more suitable for prevention than treatment.
However, there are several combination preparations also for external use, which also contain benzoyl peroxide. This, for example, is the drug “Indoxyl” (Great Britain) - it contains a combination of benzoyl peroxide 5% and the antibiotic clindamycin 1% (it costs 800 rubles per 25 g tube). And the drug Effezel (France) - it contains benzoyl peroxide 2.5% in combination with the retinoid adapalene 0.1%. This drug is already significantly more expensive than Baziron - the price for it will be at least 1,300 rubles (for a 30 g tube).
Composition and release form
Gel for external use | 100 g |
benzoyl peroxide aqueous (in terms of benzoyl peroxide anhydrous) | 2.5 g |
5.0 g | |
10.0 g | |
excipients: methacrylic acid copolymer; poloxamer 182; carbomer 940; glycerol; disodium edetate; docusate sodium; propylene glycol; colloidal silicon dioxide; sodium hydroxide; purified water |
in LDPE tubes of 40 g; in a cardboard pack 1 tube.
Indications for use of the drug Baziron:
According to the instructions, it has only 1 indication for use:
- acne.
But the fact is that the indications in the official instructions for use are written incorrectly. The fact is that the term acne can imply the presence of only non-inflammatory elements - acne vulgaris (comedones). Such non-inflammatory elements do not require the use of antimicrobial agents, but are treated only with topical retinoids (Differin, Klenzit) or drugs with azelaic acid (Skinoren, Azelac).
Preparations with benzoyl peroxide are used when there are inflammatory elements (acne). The latter can be either in the form of pustules with pus, or papules without pus. Therefore, the correct indication for the use of Baziron should be “Papulopustular acne of mild, moderate or severe degree.”
Side effect of the drug -
When using the drug, local skin irritation is possible, which is normal. Frequent symptoms of irritation include flaking and dry skin, redness, and a burning sensation. More rare symptoms include skin soreness and contact dermatitis. Rarely, allergic contact dermatitis may occur, which will require discontinuation of the drug.
In order to prevent or reduce the symptoms of irritation, we recommend that you start using Baziron AS with a 2.5% concentration of benzoyl peroxide. If symptoms of irritation do occur, then within 1-2 weeks you can switch to a single use of the drug (once a day), then returning to use 2 times a day (of course, if this was initially necessary).
Important : Benzoyl peroxide increases skin sensitivity to the sun. This means that when using the drug during periods of high solar activity, hyperpigmentation of the skin in the areas where the drug is applied is highly likely. Therefore, you will need to use sun protection products - no less than SPF 50; face-shading glasses, a Panama hat or a cap will also be useful. Let us remind you that products with SPF must be non-comedogenic (not clog pores), otherwise we will get an exacerbation of acne.
A good product SPF 50 for acne (in the form of a suspension) –
Contraindications for use –
- allergy to one of the components of the drug,
- children's age up to 12 years.
Special instructions - the drug can only be applied to the skin (not to the mucous membrane and red border of the lips). In case of contact with the mucous membranes of the nose, eyes, or mouth, rinse immediately with water. In addition, it is undesirable to use Baziron AC in parallel with products that have a drying, exfoliating effect, or alcohol-based products, because this will increase the irritant effect of the drug.
Use during pregnancy and lactation –
The drug has extremely low absorption from the surface of the skin, due to which it practically does not enter the bloodstream and does not have a systemic effect on the body. However, a large amount of breakdown products of benzoyl peroxide, namely benzoic acid, enters the body. No safety studies have been conducted during pregnancy and lactation. We hope that our article on the topic: Baziron AS price reviews was useful to you!
Sources:
1. Textbook on dermatology “Fitzpatrick's Dermatology” (8th edition), 2. “Etiology, pathogenesis, classification and clinical picture of acne vulgaris” (Barinova A.N.), 3. “Acne from the position of evidence-based medicine” (Anisimova M. .Yu.), 4. “Modern methods of treatment and rehabilitation of patients with acne vulgaris” (Barinova A.N.).
Mode of application
For acne of mild and often moderate severity, which is accompanied by comedones in combination with inflammatory processes, Baziron AS as monotherapy should be used for a long time - from 2 to 6 months. Significant improvement is usually observed after 1 month, and a lasting effect after 3 months of treatment. At the same time, in order to carefully cleanse and moisturize the skin, it is necessary to use modern non-comedogenic preparations without alcohol and other drying and irritating components.
How to apply Baziron AS
In patients with sensitive skin, it is recommended to use 2.5% (less often 5%) Baziron AS gel. It is applied 1-3 times a day in a small amount with a light touch (without rubbing) only to the affected areas of clean, dry skin. In addition, it is necessary not to forget about compliance with protective measures from exposure to sunlight and ultraviolet rays.
Produced by manufacturers in various countries, analogues of Baziron AS are not completely similar in composition, but only in the main component - benzoyl peroxide. Such analogues include "Oxygel" and "Azix-Derm" (India), "Indoxyl" (Ireland), "Proactive" (USA), "Eclaran 5" (France), "Oxy 5, 10" (UK), " Effezel" (France).
When choosing between Baziron and Differin (adapalene), you should keep in mind that, despite the different mechanisms, the results of their action are largely identical. Differin selectively binds to special receptors in the nuclei of keratinocytes and effectively regulates the processes of their final differentiation, as well as the exfoliation of plates formed by horny epithelial cells. Therefore, it is characterized by a more pronounced keratolytic effect.
Baziron AS is used for all stages of acne to carry out both the main and maintenance courses of therapy. Baziron AS is effective for comedonal and papulopustular forms of rashes, is well tolerated and is characterized by the absence of a photosensitizing effect.
At the same time, Baziron has more pronounced antimicrobial and anti-inflammatory, as well as depigmenting effects. Therefore, it is often prescribed before the use of Differin and as maintenance therapy after it, and sometimes simultaneously with Differin. In the latter case, the drug Effezel is usually used, which contains adapalene and benzoyl peroxide as the main components.
Photo taken from the resource irecommend.ru
ABOUT
The company has been producing dermatological products since 1981. It is a subsidiary of Nestle and L'Oreal. Provides its customers with high-quality medicinal cosmetics that have passed all clinical tests. The products are approved by world dermatologists.
The products entered the Russian market in 2002, where they occupied a strong niche among the pharmaceutical assortment.
The company's product range is huge. The “Baziron Control” line of products especially stands out. The product is intended for the care of acne-prone skin. It has the status of medicinal cosmetics. Restores and maintains the skin after acne treatment. Prevents the appearance of acne in the future. Used to prevent acne.
Pros of using a cosmetic line
What the Baziron Control series consists of largely explains the popularity of medicinal cosmetics. It is intended for the care of acne-prone skin. Has the following advantages:
- contains natural ingredients;
- retains moisture inside cells, moisturizes it;
- normalizes sebaceous-fat metabolism;
- has anti-inflammatory, antiseptic and antimicrobial effects;
- eliminates dryness and irritation;
- softens the dermis;
- protects the epidermis from the harmful effects of sunlight;
- restores skin after treatment;
- thoroughly cleanses the epidermis;
- prevents the appearance of acne;
- improves complexion and general skin condition.
In addition, the products are economical, do not cause allergies, are effective and easy to use. They have a large number of positive reviews from dermatologists.
Baziron: reviews of dermatologists about the drug
As we said above, reviews of Baziron AS from dermatologists allow us to deservedly classify this drug as the gold standard for the treatment of acne.
But, only as part of complex therapy! International protocols for the treatment of acne are well described in the most famous textbook on dermatology - Fitzpatrick's Dermatology (we use the 8th edition). What does this textbook tell us? 1) We have already said that acne can be of 2 types. Firstly, these are papules (without pus inside), and secondly, they are pustules with pus. A patient may have both types of acne well expressed at the same time, or one type may dominate the other. And this is very important for us, because... When prescribing a treatment regimen, we will take into account what type of inflammatory elements dominates in the patient.
2) If the patient is dominated by papules, then we will prescribe him the drug Baziron AS once a day (in the morning) + one of the topical retinoids based on adapalene. For example, it could be Differin or Clenzit (optional). Topical retinoids are also used externally once a day, but at night (24stoma.ru).
3) If the patient has pustules with pus, then this is a clear indication for using not only the combination of “benzoyl peroxide + topical retinoid”, but also adding an antibiotic. For mild to moderate severity, the antibiotic is prescribed externally; for severe acne, it is prescribed orally. Thus, for mild to moderate severity, we must use a combination of drugs. And here there are many possible combinations of different drugs.
For example, we can still use the drug Baziron AS 1 time a day (in the morning) + the drug Klenzit-S in the evening (it contains the retinoid adapalene + the antibiotic clindamycin). Another option may involve the use not of Baziron, but of combination drugs where benzoyl peroxide is combined with antibiotics or retinoids. Examples of combination drugs for acne treatment:
- Indoxyl (UK) – benzoyl peroxide 5% + clindamycin 1%.
- Effezel (France) – benzoyl peroxide 2.5% + retinoid adapalene 0.1%.
Those. we can, for example, use the combination drug Indoxyl once a day (in the morning), and in the evening use one of the topical retinoids (Differin or Clenzit - to choose from). Another option is that we can use the combined drug Effezel once a day (in the evening), but in the morning of that day we then have to use one of the antibiotic gels - it could be Dalatsin, Clindavit or others. As you can see: the abundance of different drugs gives us room for maneuver.
Important: But we want to assure you that acne treatment is not limited to just prescribing benzoyl peroxide, topical retinoids or antibiotics. Phototherapy, laser treatment, and in women, oral contraceptives to reduce the production of androgens can play a major role in treatment. You can read about all these methods using the links below.
→ International acne treatment protocols → Acne treatment protocols
Baziron AS product
Baziron®️ AS is an antibacterial, anti-inflammatory drug for external use. Effective in destroying bacteria that provoke the development of acne and acne Propionibacterium acnes, Staphylococcus epidermidis. By reducing skin oiliness, it prevents the occurrence of comedones.
Gel Baziron®️ AC for acne gives you self-confidence and a feeling of harmony with the world around you.
Composition of Baziron®️ AC gel
Baziron®️ AC gel contains benzoyl peroxide, an active substance that was specially developed to combat bacteria, an important cause of acne. Baziron®️ AS has been proven to kill 94% of acne-causing bacteria within just 1 week of use, for which the gel can be called an “ambulance” for acne.
In addition to fighting bacteria, Baziron®️ AS also regulates the functioning of the sebaceous glands (helps get rid of oily sheen) and normalizes oxygen supply to the skin. And what is especially important is that Baziron®️ AS is not an antibiotic, so this gel retains its effect over time, the skin “does not get used to the drug” (resistance (resistance) of bacteria to the effects of the drug does not develop).
And although Baziron®️ AS, a medicinal gel for acne, is sold in pharmacies without a doctor’s prescription, clinicians around the world have thoroughly studied this drug, which is included in both Russian and European clinical recommendations for the treatment of patients with acne for dermatologists.